生物医药

1. 新型超支化聚合物（聚磷酸酯、多肽等）设计、合成及生物医药应用研究2. 特种功能高分子（可溶性聚酰亚胺等）设计、合成及应用研究

Self-assembly;Hyperbranched Polymers;Glycyrrhetinic Acid;Drug Delivery;Polyimide;Immunopet;Polyimides;Transparency;Optical Coherence Tomography;Hyperbranched Polymer

1. Liu Jinyao; Pang Yan; Zhu Zhaoyang; Wang Dali; Li Chunting; Huang Wei; Zhu Xinyuan; Yan, Therapeutic Nanocarriers with Hydrogen Peroxide-Triggered Drug Release for Cancer Treatment, Biomacromolecules, 2013, 14, 1627.
2. Tao Wei; Liu Yong; Jiang Binbin; Yu Songrui; Huang Wei; Zhou Yongfeng; Yan Deyue, A Linear-Hyperbranched Supramolecular Amphiphile and Its Self-Assembly into Vesicles with Great Ductility, JACS, 2012, 134, 762.
3. Liu Jinyao, Pang Yan, Chen Jun, Huang Ping, Huang Wei, Zhu Xinyuan, Yan Deyue, Hyperbranched polydiselenide as a self assembling broad spectrum anticancer agent, Biomaterials, 2012, 33, 7765.
4. Liu Jinyao; Huang Wei; Pang Yan; Huang Ping; Zhu Xinyuan; Zhou Yongfeng; Yan Deyue, Molecular Self-Assembly of a Homopolymer: An Alternative To Fabricate Drug-Delivery Platforms for Cancer Therapy, Angew. Chem. Int. Ed., 2011, 50, 9162.
5. Zhou Yongfeng, Huang Wei, Liu Jinyao, Zhu Xinyuan, Yan Deyue, Self-Assembly of Hyperbranched Polymers and Its Biomedical Applications, Advanced Materials, 2010, 22, 4567.
6. Liu Jinyao, Huang Wei, Pang Yan, Zhu Xinyuan, Zhou Yongfeng, Yan Deyue, The in vitro biocompatibility of self-assembled hyperbranched copolyphosphate nanocarriers, Biomaterials, 2010, 31, 5643.
7. Liu Jinyao, Pang Yan, Huang Wei, Zhu Xinyuan, Zhou Yongfeng, Yan Deyue, Self-Assembly of phospholipid-analogous hyperbranched polymers nanomicelles for drug delivery, Biomaterials, 2010, 31, 1334.
8. Liu Jinyao, Huang Wei, Zhou Yongfeng, Yan Deyue, Synthesis of Hyperbranched Polyphosphates by Self-Condensing Ring-Opening Polymerization of HEEP without Catalyst, Macromolecules, 2009, 42, 4394.
9. Zhang Yongwen, Peng Huashong, Huang Wei, Zhou Yongfeng, Zhang Xuehong, Yan Deyue, Hyperbranched poly(amidoamine) as the stabilizer and reductant to prepare colloid silver nanoparticles in situ and their antibacterial activity, Journal of Physical Chemistry C, 2008, 112, 2330.
10. Zhang Yongwen, Huang Wei, Zhou Yongfeng, Yan Deyue, A physical gel made from hyperbranched polymer gelator, Chem. Commun., 2007, 25, 2587.

1. 环氧树脂的制备方法
上海交通大学; 浙江豪邦化工有限公司
黄卫; 吴修明; 汪羽翎; 颜德岳; 于春阳; 吴京春; 林锦堂
公开日期: 2024-03-19 申请日期: 2023-12-13 公开号: CN117720706A

2. Ketone carbonyl-containing hydrophobic antitumor drug and conjugate thereof as well as nano preparation containing conjugate, preparation method therefor, and application thereof
Jiangsu Jibeier Pharmaceutical Co. Ltd.
Zhongyi Geng; Xinyuan Zhu; Wei Huang; Deyue Yan; Yao Wang; Yongfeng Zhou
公开日期: 2023-12-05 申请日期: 2019-03-05 公开号: US11833128B2

3. AFFIBODY-CYTOTOXIN CONJUGATE FOR ACTIVE TARGETED THERAPY OF TUMORS, NANOPARTICLE THEREOF, PREPARATION METHOD THEREOF AND APPLICATION THEREOF
SHANGHAI JIAOTONG UNIVERSITY
Deyue YAN; Xiaoxia XIA; Xuelin XIA; Xiaoyuan YANG; Wei HUANG
公开日期: 2023-10-05 申请日期: 2021-02-05 公开号: US20230310624A1

4. AFFIBODY-CYTOTOXIN CONJUGATE USED FOR ACTIVE TUMOR TARGETING THERAPY, AND NANOPARTICLES, PREPARATION METHOD, AND APPLICATION THEREOF
SHANGHAI JIAOTONG UNIVERSITY
YAN Deyue; XIA Xiaoxia; XIA Xuelin; YANG Xiaoyuan; HUANG Wei
公开日期: 2023-08-23 申请日期: 2021-02-05 公开号: EP4230224A1

5. 同源性癌细胞膜包被的核酸-化疗药物复合物纳米粒子
上海交通大学
颜德岳; 朱利娟; 陈天保; 徐杰; 黄卫
公开日期: 2023-05-26 申请日期: 2022-04-02 公开号: CN114869858B

6. 用于肿瘤免疫/靶向性治疗的PD-1蛋白-细胞毒素偶联物及其制备方法、应用
上海交通大学
颜德岳; 夏雪霖; 夏小霞; 黄卫; 杨晓媛
公开日期: 2023-03-17 申请日期: 2022-08-23 公开号: CN115806630A

7. 用于肿瘤主动靶向治疗的两亲性前药及其纳米颗粒的制备方法、应用
上海交通大学
夏雪霖; 王冠春; 杨晓媛; 黄平; 黄卫; 颜德岳
公开日期: 2022-04-01 申请日期: 2020-01-17 公开号: CN111097052B

8. Amphiphilic drug-drug conjugates for cancer therapy, compositions and methods of preparation and uses thereof
Shanghai Jiao Tong University
Ping Huang; Yongfeng Zhou; Deyue Yan; Xinyuan Zhu; Wei Huang
公开日期: 2021-03-30 申请日期: 2019-09-30 公开号: US10960078B2

9. KETONE CARBONYL-CONTAINING HYDROPHOBIC ANTITUMOR DRUG AND CONJUGATE THEREOF AS WELL AS NANO PREPARATION CONTAINING CONJUGATE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
Jiangsu Jibeier Pharmaceutical Co. Ltd.
GENG, Zhongyi; ZHOU, Yongfeng; ZHU, Xinyuan; WANG, Yao; YAN, Deyue; HUANG, Wei
公开日期: 2021-01-13 申请日期: 2019-03-05 公开号: EP3763391A1

10. KETONE CARBONYL-CONTAINING HYDROPHOBIC ANTITUMOR DRUG AND CONJUGATE THEREOF AS WELL AS NANO PREPARATION CONTAINING CONJUGATE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
Jiangsu Jibeier Pharmaceutical Co. Ltd.
Deyue Yan; Zhongyi Geng; Yao Wang; Xinyuan Zhu; Wei Huang; Yongfeng Zhou
公开日期: 2021-01-07 申请日期: 2019-03-05 公开号: US20210000785A1

11. AMPHIPHILIC DRUG-DRUG CONJUGATES FOR CANCER THERAPY, COMPOSITIONS AND METHODS OF PREPARATION AND USES THEREOF
Shanghai Jiao Tong University
Deyue Yan; Xinyuan Zhu; Wei Huang; Ping Huang; Yongfeng Zhou
公开日期: 2020-01-23 申请日期: 2019-09-30 公开号: US20200023066A1

12. Amphiphilic drug-drug conjugates for cancer therapy, compositions and methods of preparation and uses thereof
Shanghai Jiao Tong University
Deyue Yan; Ping Huang; Xinyuan Zhu; Wei Huang; Yongfeng Zhou
公开日期: 2019-11-05 申请日期: 2016-11-15 公开号: US10463743B2

13. PREPARATION AND APPLICATION OF AMPHIPHILIC DRUG-DRUG NANOPARTICLE FOR REVERSING PLATINUM-BASED ANTICANCER DRUG RESISTANCE IN CANCER THERAPY
UNIV SHANGHAI JIAOTONG
XU SHUTING; YAN DEYUE; HUANG WEI; ZHU XINYUAN; ZHOU YONGFENG
公开日期: 2018-07-26 申请日期: 2018-01-08 公开号: WO2018133687A1

14. 含叔丁基、醚键和双酚A结构可溶性聚酰亚胺及制备方法
上海交通大学
李从严; 伊朗; 徐舒婷; 李纯婷; 李传龙; 黄卫; 颜德岳
公开日期: 2018-05-01 申请日期: 2015-12-02 公开号: CN105542163B

15. 用于乏氧肿瘤治疗光诱导自产氧气、单线态氧和活性二价铂的纳米前药及其制备方法、应用
上海交通大学
徐舒婷; 颜德岳; 朱新远; 黄卫; 周永丰
公开日期: 2017-11-24 申请日期: 2017-07-26 公开号: CN107375927A

16. 用于逆转肿瘤对铂类抗癌药多药耐药性的两亲性药‑药纳米颗粒药物及其制备方法与应用
UNIV SHANGHAI JIAOTONG
HUANG WEI; XU SHUTING; ZHU XINYUAN; YAN DEYUE; ZHOU YONGFENG
公开日期: 2017-06-20 申请日期: 2017-01-18 公开号: CN106860872A

17. 用于逆转肿瘤对铂类抗癌药多药耐药性的两亲性药‑药纳米颗粒药物及其制备方法与应用
UNIV SHANGHAI JIAOTONG
HUANG WEI; XU SHUTING; ZHU XINYUAN; YAN DEYUE; ZHOU YONGFENG
公开日期: 2017-06-20 申请日期: 2017-01-18 公开号: CN106860872A

18. 一种具有逆转肿瘤多药耐药性功能的两亲性缀合物抗肿瘤纳米药及其制备方法和应用
上海交通大学
颜德岳; 黄平; 朱新远; 周永丰; 黄卫
公开日期: 2017-05-10 申请日期: 2016-12-13 公开号: CN106620717A

19. AMPHIPHILIC DRUG-DRUG CONJUGATES FOR CANCER THERAPY, COMPOSITIONS AND METHODS OF PREPARATION AND USES THEREOF
UNIV SHANGHAI JIAOTONG
YAN DEYUE; HUANG PING; ZHU XINYUAN; HUANG WEI; ZHOU YONGFENG
公开日期: 2017-03-02 申请日期: 2016-11-15 公开号: US2017056506A1

20. Amphiphilic drug-drug conjugates for cancer therapy, compositions and methods of preparation and uses thereof
UNIV SHANGHAI JIAOTONG
ZHOU YONGFENG; YAN DEYUE; HUANG PING; ZHU XINYUAN; HUANG WEI
公开日期: 2017-01-03 申请日期: 2014-03-11 公开号: US9533054B2

主持和参加国家自然科学基金面上项目和重点项目、973计划项目、上海市自然科学重点项目等多项课题研究。

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