论文著作：
(1) Han Yinlei, Yin Huanhuan, Li Chen, Du Jiangyue, He Yi*, Guan Yixin*, Discovery of new pentapeptide inhibitors against amyloid-β aggregation using Word2Vec and molecular simulation, ACS Chemical Neuroscience, 2025, 16, 1055-1065
(2) Zhang Qin, Feng Yahui, Liang Xiyu, Wu Shuming, He Fang, Guan Yixin*, Wang Zhongqing*, Efficient bio-reduction of 3-nitro phthalic acid using engineered nitroreductase and V2O5, Process Biochemistry, 2025, 148, 157-167
(3) Huang Hao, Zhang Haoyu, Du Ningjie, Lyu Yidan, Xu Jiahang, Fu Haoran*, Guan Yixin*, Nan Kewang*, Drug origami: A computation-guided approach for customizable drug release kinetics of oral formulations, Matter, 2025, 8, 101878
(4) Du Ningjie, Fan Yunlong, Zhang Yunting, Huang Hao, Lyu Yidan, Cai Ruisi, Zhang Yuqi, Zhang Tianyuan, Guan Yixin*, Nan Kewang*, Wireless, programmable, and refillable hydrogel bioelectronics for enhanced diabetic wound healing, Advanced Science, 2024, 11, 2407820
(5) Du Ningjie, Fan Yunlong, Huang Hao, Guan Yixin*, Nan Kewang*, Stimuli-responsive hydrogel actuators for skin therapeutics and beyond, Soft Science, 2024, 4, 35
(6) Wang Dong, Wang Jing, Wu Yingchao, Liu Caixia, Huang Yuzhe, Chen Yan, Ding Zhifeng, Guan Yixin, Wu Qingxi, Amelioration of acute alcoholic liver injury via attenuating oxidative damage and modulating inflammation by means of ursodeoxycholic acid−zein nanoparticles, Journal of Agricultural and Food Chemistry, 2023, 71, 17080-17096
(7) Han Yinlei, Yin Huanhuan, Xiao Chao, Matthew T. Bernards, He Yi*, Guan Yixin*, Understanding the molecular mechanisms of polyphenol inhibition of amyloid β aggregation, ACS Chemical Neuroscience, 2023, 14, 4051-4061
(8) Yin Huanhuan, Han Yinlei, Yan Xiao*, Guan Yixin*, Hematoxylin modulates tau-RD protein fibrillization and ameliorates Alzheimer's disease-like symptoms in a yeast model, International Journal of Biological Macromolecules, 2023, 250, 126140
(9) Wang Zidan, Peng Huhong, Lin Dongqiang, Guan Yixin*, Exploring the effect of different linkers on self-assembly, ROS-sensitivity and anticancer efficacy of hydroxyethyl starch-curcumin prodrug, Carboyhydrate Polymer Technologies and Applications, 2023, 5, 100324
(10) Zhang Yipeng, Wang Liying, Wang Zidan, Zhou Quan, Zhou Xuefei, Zhou Tianhua, Guan Yixin, Liu Xiangrui, Surface-anchored microbial enzyme-responsive solid lipid nanoparticles enabling colonic budesonide release for ulcerative colitis treatment, Journal of Nanobiotechnology, 2023, 21, 145
(11) Yin Huanhuan, Han Yinlei, Yan Xiao*, Guan Yixin*, Proanthocyanidins prevent tau protein aggregation and disintegrate tau filaments, Chinese Journal of Chemical Engineering, 2023, 57, 63-71
(12) Rui Jinzhou, Peng Huhong, Guan Yixin*, Yao Shanjing, Preparation of ROS-responsive drug-loaded hydrogels applied in wound dressings using supercritical solvent impregnation, The Journal of Supercritical Fluids, 2022, 188, 105682
(13) Wang Zidan, Peng Huhong, Guan Yixin*, Yao Shanjing, Supercritical CO2 assisted micronization of curcumin-loaded oil-in-water emulsion promising in colon targeted delivery, Journal of CO2 Utilization, 2022, 59, 101966
(14) Peng Huhong, Wang Zidan, Guan Yixin*, Yao Shanjing, Supercritical CO2 assisted preparation of chitosan-based nano-in-microparticles with potential for efficient pulmonary drug delivery, Journal of CO2 Utilization, 2021, 46, 101486
(15) Xiao Xia, He Jingkai, Guan Yixin*, Yao Shanjing, Effect of cholinium amino acids ionic liquids as cosolvents on the bioconversion of phytosterols by Mycobacterium sp. resting cells, ACS Sustainable Chemistry & Engineering, 2020, 8, 17124-17132
(16) Wu Qingxi, Wang Zidan, Zheng Mengfei, Su Ting, Wang Xiaohui, Guan Yixin, Chen Yan, Development of metformin hydrochloride loaded dissolving tablets with novel carboxymethylcellulose/poly-L-lysine/TPP complex, International Journal of Biological Macromolecules, 2020, 155, 411-420
(17) Peng Huhong, Hong Dongxiao, Guan Yixin*, Yao Shanjing, Preparation of pH-responsive DOX-loaded chitosan nanoparticles using supercritical assisted atomization with an enhanced mixer, International Journal of Pharmaceutics, 2019, 558, 82-90
(18) Wu Qingxi, Guan Yixin, Yao Shanjing, Sodium cellulose sulfate: A promising biomaterial used for microcarriers' designing, Frontiers of Chemical Science and Engineering, 2019, 13, 46-58
(19) Guan Jintao, Han Chaofei, Guan Yixin*, Zhang Songhong, Yun Junxian*, Yao Shanjing, Optimizational production of phenyllactic acid by a Lactobacillus buchneri strain via uniform design with overlay sampling methodology, Chinese Journal of Chemical Engineering, 2019, 27, 418-425
(20) Chen Chuanxin, Peng Huhong, Guan Yixin*, Yao Shanjing, Morphological study on the pore growth profile of poly(_x0002_ε-caprolactone) bi-modal porous foams using a modified supercritical CO2 foaming process, The Journal of Supercritical Fluids, 2019, 143, 72-81
(21) Hong Dongxiao, Yun Yulong, Guan Yixin*, Yao Shanjing, Preparation of micrometric powders of parathyroid hormone (PTH1-34)-loaded chitosan oligosaccharide by supercritical fluid assisted atomization, International Journal of Pharmaceutics, 2018, 545, 389-394
(22) Guan Jintao, Guan Yixin*, Yun Junxian*, Yao Shanjing, Chromatographic separation of phenyllactic acid from crude broth using cryogels with dual functional groups, Journal of Chromatography A, 2018, 1554, 92-100
(23) Xin Xin, Guan Yixin*, Yao Shanjing, Sustained release of dexamethasone from drug-loading PLGA scaffolds with specific pore structure fabricated by supercritical CO2 foaming, Journal of Applied Polymer Science, 2018, 135, 46207
(24) Xin Xin, Guan Yixin*, Yao Shanjing, Bi-/multi-modal pore formation of PLGA/hydroxyapatite composite scaffolds by heterogeneous nucleation in supercritical CO2 foaming, Chinese Journal of Chemical Engineering, 2018, 26, 207-212
(25) Yuan Junjie, Guan Yixin*, Yao Shanjing, Evaluation of biocompatible ionic liquids for their application in phytosterols bioconversion by Mycobacterium sp. resting cells, ACS Sustainable Chemistry & Engineering, 2017, 5, 10702-10709
(26) Chen Chuanxin, Liu Qianqian, Xin Xin, Guan Yixin*, Yao Shanjing, Pore formation of poly(_x0002_ε-caprolactone) scaffolds with melting point reduction in supercritical CO2 foaming, The Journal of Supercritical Fluids, 2016, 117, 279-288
(27) Yuan Junjie, Guan Yixin*, Wang Yanting, Wang Haiqing, Yao Shanjing, Side-chain cleavage of phytosterols by Mycobacterium sp. MB 3683 in a biphasic ionic liquid/aqueous system, Journal of Chemical Technology and Biotechnology, 2016, 91, 2631-2637
(28) Xin Xin, Liu Qianqian, Chen Chuanxin, Guan Yixin*, Yao Shanjing, Fabrication of bimodal porous PLGA scaffolds by supercritical CO2 foaming/particle leaching technique, Journal of Applied Polymer Science, 2016, 33, 43644
(29) Shen Yubin, Du Zhe, Tang Chuan, Guan Yixin, Yao Shanjing, Formulation of insulin-loaded N-trimethyl chitosan microparticles with improved efficacy for inhalation by supercritical fluid assisted production, International Journal of Pharmaceutics, 2016, 505, 223-233
(30) Shen Yubin, Guan Yixin, Yao Shanjing, Supercritical fluid assisted production of micrometric powders of the labile trypsin and chitosan/trypsin composite microparticles, International Journal of Pharmaceutics, 2015, 489, 226-236
关怡新
浙江省
研究领域：
精细化工,生物医药
研究方向：
· 生物制药技术
· 生物催化和转化
· 蛋白质工程
所在单位：
浙江大学
