生物医药

1. 微生物天然产物（药物）的挖掘；
2. 微生物天然产物生物合成机制；
3. 化学酶法合成重要药物及其中间体。

奥运会;契机;旅游业

1. Haoyang Liu, Hailiang Xing, Peilan Yu, Yanjie Wang, Jia-Lei Yan, Junyang Liu,* Min Wang*. Base-Controlled Synthesis of Heteroatom-Embedded Membered Cycloalkynes and Membered Sultams through Copper-Catalyzed Cyclization[J]. J Org Chem, 2025, 90, 2, 984-993.
2. Yue Tang, Xiaoying Tian, Min Wang, Yinglu Cui, Yang She, Zhaoxiang Shi, Jiaqi Liu, Huijin Mao, Lilu Liu, Chao Li, Yuwei Zhang, Pengwei Li, Yue Ma, Jinyuan Sun, Qing Du, Jie Li, Jun Wang, De-feng Li, Bian Wu*, Feng Shao*, Yihua Chen*. The β-D-manno-heptoses are immune agonists across kingdoms[J]. Science, 2024, 385, 678-684.
3. Yunqiang Wu, Min Wang*, Liwei Liu*. Advances on structure, bioactivity, and biosynthesis of amino acid-containing trans-AT polyketides[J]. Eur J Med Chem, 2023, 262, 115890.
4. Yuwei Zhang#, Ge Liao#, Min Wang#, Zhao Zhang#, Liwei Liu, Yuqin Song, Dacheng Wang, Tingting Hao, Jie Feng, Bin Xia, Yixiang Wang, Xiaoyu Tang*, Yihua Chen*. Human associated bacteria adopt an unusual route for synthesizing ;acetylated tetramates for environmental adaptation[J]. Microbiome, 2023, 11: 97.
5. Peishan Li#, Hongmei Lu#, Yanzhu Zhang, Xuejiao Zhang, Lianliang Liu, Min Wang*, Liwei Liu*. The natural products discovered in marine sponge-associated microorganisms: structures, activities, and mining strategy[J]. Front Mar Sci, 2023, 10: 1191858.
6. Li Tao#, Min Wang#, Guobo Guan, Yuwei Zhang, Tingting Hao, Chao Li, Shuaihu Li, Yihua Chen, Guanghua Huang*. Streptococcus mutans suppresses filamentous growth of Candida albicans through secreting mutanocyclin, an unacylated tetramic acid[J]. Virulence, 2022, 13:1, 542-557.
7. Yue Tang#, Min Wang#, Hua Qin, Xiangxiang An, Zhengyan Guo, Guoliang Zhu, Lixin Zhang, and Yihua Chen*. Deciphering the Biosynthesis of TDP-β-L-oleandrose in Avermectin[J]. J Nat Prod, 2020, 83: 3199-3206.
8. Min Wang#, Zhoujie Xie#, Shoubin Tang#, Ee Ling Chang, Yue Tang, Zhengyan Guo, Yinglu Cui, Bian Wu, Tao Ye, Yihua Chen*. Reductase of mutanobactin synthetase triggers sequential C-C macrocyclization, C-S bond formation, and C-C bond cleavage[J]. Org Lett, 2020, 22: 960-964.
9. Jine Li#, Min Wang#, Yong Ding, Yue Tang, Zhiguo Zhang*, Yihua Chen*. Involvement of an octose ketoreductase and two acyltransferases in the biosynthesis of paulomycins[J]. Sci Rep, 2016, 6: 21180.
10. Tao Ji#, Yanjie Wang#, Min Wang#, Ben Niu#, Ping Xie, Charles U. Pittman, Jr., and Aihua Zhou*. Parallel syntheses of eight-membered ring sultams via two cascade reactions in water[J]. Acs Comb Sci, 2013, 15: 595-600.
11. Min Wang, Yanjie Wang, Xueyong Qi, Guohua Xia, Kun Tong, Jinchang Tu, Charles U. Pittman Jr., and Aihua Zhou*. Selective synthesis of seven- and eight-membered ring sultams via two tandem reaction protocols from one starting material[J]. Org Lett, 2012, 14: 3700-3703.

1. 陈义华，唐越，王敏。一类保罗霉素衍生物及其制备方法与应用（ZL201810677960.X）。
2. 刘磊，陈天鸽，徐巨才，许敏，徐振岗，陈韬文，干雨泽，魏萍，王敏，袁兆栋，贺天懿。具有缓释维生素作用的特殊医学用途配方食品的加工方法（CN 117158578 B）。
3. 刘君羊，刘昊洋，邢海亮，王敏。一种六元环磺酰胺类化合物的制备方法202410937674。

1. 微生物资源前期开发国家重点实验室前沿探索课题基金：糖苷类化合物α、β构象转换的研究，项目负责人，2019-2020。
2. 中国科学院微生物研究所科学研究基金：N-糖苷键构象的转换及其机制的研究，项目负责人，2018-2021。
3. 国家自然科学基金青年科学基金项目：阿维菌素中L-齐墩果糖的生物合成机制研究（项目号：31700036），项目负责人，2018.01-2020.12。
4. 企业横向项目：五肽荧光标签的添加与结构表征，项目负责人，2024-2025。
5. 农业农村部植保生物技术重点实验室开放基金项目：抗小麦病毒农药先导化合物的挖掘，项目负责人，2024-2025。

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