精细化工

1、精细化学品的分离与精制：
利用溶液结晶和熔融结晶等手段绿色高效纯化医药、农药及聚合单体等精细化学品，并对晶体产品粉体质量（粒度、形貌等）进行调控。
2、结晶分子机理研究：
利用实验和模拟相结合的手段，探究溶液结晶过程的分子组装规律及成核机制。

1. Yu Liu, Lina Jia; Songgu Wu, Shijie Xu, Xu Zhang, Shuang Jiang, Junbo Gong. Polymorphism and molecular conformations of nicosulfuron: structure, properties and desolvation process. CrystEngComm，2019, 21, 2790-2798.
2. Yu Liu, Shijie Xu, Xu Zhang, Weiwei Tang, Junbo Gong. Unveiling the Critical Roles of Aromatic Interactions in the Crystal Nucleation Pathway of Flufenamic Acid. Cryst. Growth Des., 2019, 19, 12, 61(3).
3. Yu Liu, Xu Zhang, Mengwei Wang, Yiming Ma, Weiwei Tang. Uncovering the effect of solvents on solid-liquid phase equilibrium of praziquantel, J. Mol. Liq., 2020, 297, 1.
4. Yu Liu, Xu Zhang, Lina Zhou, Shichao Du, Songgu Wu, and Junbo Gong., Development and Structure Analysis of Crystal Forms of Apabetalone. Cryst. Growth Des., 2021, 21, 3864-3873.
5. Yu Liu, Peng Yang, Keke Zhang, Jun Xu, Songgu Wu, and Junbo Gong., Bendable and twistable crystals of flufenamic acid form III with bending Mechanofluorochromism Behavior. Cryst. Growth Des., 2022,22,1312-1318.
6. Yu Liu, Caiyun Ma, Junbo Gong and Kevin J. Roberts., The influence of solvent selection upon the crystallisability and nucleation kinetics tolfenamic acid form II. Cryst. Growth Des. 2023, 23, 5486-5859.
7. Mengwei Wang, Yu Liu, Shichao Du, Yanxiao Zhao, Peiyi Li, Determining the solubility and understanding the solid-liquid equilibrium behavior of cyhalothric acid in eleven pure solvents, J. Mol. Liq., 2020, 300, 112365.
8. Bo Lin, Yu Liu，Mengwei Wang, Yan Wang, Shichao Du, JunBo Gong, and Songgu Wu. Intermolecular Interactions and Solubility Behavior of Multicomponent Crystal Forms of Orotic Acid: Prediction and Experiments. Cryst. Growth Des., 2021,21,3,1473-1481.
9. Keke Zhang, Changquan Calvin Sun, Yu Liu, Chenguang Wang, Png Shi, Jun Xu, Songgu Wu, and Junbo Gong. Structural Origins of Elastic and 2D Plastic Flexibility of Molecular Crystals Investigated with Two Polymorphs of Conformationally Rigid Coumarin. Chem. Mater., 2021, 33, 3, 1053−1060.

1.龚俊波，刘裕, 王静康等，烟嘧磺隆的一种晶型的晶体及其制备方法，CN108299392B。
2.龚俊波，刘裕, 王静康等，一种烟嘧磺隆的晶型及其制备方法，CN107954984B。
3.龚俊波，刘裕, 黄嘉骏等，一种Apabetalone晶型及其制备方法，CN109824608A。
4.龚俊波，刘裕, 黄嘉骏等，一种Apabetalone水合物晶型及其制备方法，CN109897009A。

1.国家自然科学基金面上项目“有机药物多晶型形成的分子机制及其机械性能影响规律研究”，参与。

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