精细化工

1.金属有机化学
2.药物化学
3.不对称催化
4.主族化学
5.有机硅合成

Cycloaddition;Heterocycles;Strained Molecules;Rhodium;Rhodium-catalyzed Reactions;Bridged Rings;Chiral Catalysts;Chirality;Chirality Transfer;Asymmetric Catalysis

湖南大学工作期间
56. Feng Wu,† Ji-Jie Wang,† Yuanjiu Xiao,† Quanxin Peng, Yu-Jie Li, Keren Peng, Qianlan Han, Mengran Wei, Yu Qian,* Wei Zhang,* Guoqiang Wang,* and Jian-Jun Feng*
Nat. Chem. 2025, accepted in principle.
55. Feng Wu,† Quanxin Peng,† Yu-Jie Li,† Yuanjiu Xiao, and Jian-Jun Feng*
ChemRxiv 2025, DOI: 10.26434/chemrxiv-2025-bdj32, posted on 29 August 2025
54. 冯见君教授入选中国化学会创办的高水平旗舰期刊 CCS Chemistry 2025年第7期“作者聚焦”访谈
（Author Spotlight：Jian-Jun Feng ）
CCS Chem. 2025, 7, 1882–1888.
53. Heng-Xian He,+ Xue-Chun Yang,+ Yuanjiu Xiao,+ Lei Tang, Wen-Li Xu and Jian-Jun Feng*
Sci. China Chem. 2025, DOI: 10.1007/s11426-025-2941-2
52. Xin-Yu Gao,+ Yuanjiu Xiao,+ Quanxin Peng,+ Fujian Yang, Daojing Li, Guoqiang Wang,* Yu Qian* and Jian-Jun Feng*
Rapid and Modular Access to All-Carbon Quaternary Center-Containing 2,2-Disubstituted Bicyclo[1.1.1]pentanes via Cyanocarbene Addition to Bicyclo[1.1.0]butanes
Angew. Chem. Int. Ed. 2025, e202513768
Highlighted in 化学身边学
化学深耕堂，研之成理& CBG
ChemRxiv 2025, DOI: 10.26434/chemrxiv-2025-qr3kh, posted on 24 June 2025
51. Feng Wu,+ Yuanjiu Xiao,+ Mengran Wei,+ Guoqiang Wang* and Jian-Jun Feng*
Lewis acid catalyzed enantioselective dearomative (3+2) cycloaddition of benzazoles with bicyclobutanes
Submitted
50. Heng-Xian He,+ Feng Wu,+ Kun-Ju Wang, Lei Wang and Jian-Jun Feng*
Diastereoselective synthesis of multi-substituted cyclobutanes via catalyst-controlled regiodivergent hydrophosphination of acyl bicyclobutanes
Nat. Commun., 2025, 16, 6639.   Highlighted in 化学深耕堂
Highlighted in 化学身边学
X-MOL 资讯
49. Jin-Lan Zhou,‡ Xuan Zhan,‡ Heng-Xian He,‡ Youzhi Xu, Quanxin Peng, Genping Huang,* Jian-Jun Feng*
Catalytic Activation of Acceptor-Acceptor Bicyclobutanes Enabled by Lewis Base Catalysis
Angew. Chem. Int. Ed. 2025, e202507590
Dedicated to the 99th anniversary of Hunan University.
Highlighted in 化学深耕堂   Highlighted in  WileyChem
X-MOL
48. Yuanjiu Xiao,+ Lei Tang,+ Xue-Chun Yang, Ning-Yi Wang, Jian Zhang, Wei-Ping Deng,* Jian-Jun Feng*
Catalytic Asymmetric Strategies for Bicyclo[1.1.0]butane Transformations: Advances and Applications. (Invited MiniReview by Prof. Qi-Lin Zhou（周其林院士）)
CCS Chem. 2025, 7, 1903–1934
DOI: 10.31635/ccschem. 025.202505825
Highlighted in 化学深耕堂
47. Lei Tang, Wenjuan Bai, Kun-Ju Wang, Feng Wu, Quanxin Peng, Genping Huang,* Jian-Jun Feng*
Lewis Acid Catalyzed Enantioselective (4+3)/Thia-(3+2) Cycloadditions of Bicyclobutanes and Enaminothiones: Catalyst-Directed Divergent Synthesis of Bridged Sulphur-Heterocycles.
ACS Catal. 2025, 15, 7877−7890.
被《Organic Process Research & Development》期刊列入工艺研发化学家与工程师关注要点“Some Items of Interest to Process R&D Chemists and Engineers”
Org. Process Res. Dev. 2025, 29, 1625−1634.
Highlighted in Synfacts 2025,21, 671.
Highlighted in 化学深耕堂
46. Kun Deng,+ Xue-Chun Yang,+ Jian-Jun Feng*, Zhaofeng Wang,*
Lewis Acid Catalyzed Tandem Difunctionalization/Fragmentation Reactions of Bicyclobutanes: Access to 2-Vinylidenyl 1,4-Dicarbonyl Compounds
Submitted.
45. Xue-Chun Yang,+ Ji-Jie Wang,+ Yuanjiu Xiao,* Jian-Jun Feng*
Catalytic Asymmetric Synthesis of Chiral Caged Hydrocarbons as Arenes Bioisosteres. (Invited MiniReview)
Angew. Chem. Int. Ed. 2025, 64, e202505803
Dedicated to Professor Shu-Li You and Professor Daniel B. Werz on the occasion of their 50th birthday
Highlighted in  WileyChem     and X-MOL
44. Xin-Yu Gao,+ Yuanjiu Xiao,+ Xuan Zhan, Yu-Jie Li, Kun-Ju Wang, Jian-Jun Feng*
2025 Organic Chemistry Frontiers HOT articles   Highlighted in Frontiers Journals
43. Lei Tang, Kun-Ju Wang, Lei Wang, Fujian Yang, Quanxin Peng, Guoqiang Wang*  and Jian-Jun Feng*
Science China Chemistry 2025, DOI:10.1007/s11426-025-2698-2
Highlighted in 中国科学化学       Highlighted in 化学深耕堂
42. Heng-Xian He, Feng Wu, Xu Zhang and Jian-Jun Feng*
Ring Expansion toward Fused Diazabicyclo[3.1.1]heptanes through Lewis Acid Catalyzed Highly Selective C−C/C−N Bond Cross-Exchange Reaction between Bicyclobutanes and Diaziridines
Angew. Chem. Int. Ed. 2025, 64, e202416741 （Hot Paper）
Highlighted in“CBG 咨讯-人物与科研”
X-MOL        WileyChem
被《有机化学》亮点评述 （张键，邓卫平， Chin. J. Org. Chem. 2025, 45, 367-369）
41. Wen-Biao Wu,‡ Bing Xu,‡ Xue-Chun Yang,‡ Feng Wu, Heng-Xian He, X. Zhang and Jian-Jun Feng*
Enantioselective formal (3+3) cycloaddition of bicyclobutanes with nitrones enabled by asymmetric Lewis acid catalysis
Nat. Commun., 2024, 15, 8005.
Highlighted in 研之成理
Enantioselective formal [4π+2σ] cycloaddition of bicyclobutanes with nitrones enabled by asymmetric Lewis acid catalysis
Research Square, Posted Date: June 18th, 2024
DOI:https://doi.org/10.21203/rs.3.rs-4542058/v1
40. Yongqing Kuang *, Jie Liu, Jian-Jun Feng, Wen Yang, Shuanglian Cai, Ling Shi
由4-羟基苯乙酮制备对乙酰氨基酚的两步合成实验设计
Experimental Design for the Two-Step Synthesis of Paracetamol from 4-Hydroxyacetophenone
大学化学 Univ. Chem. 2024, 39 (8), 331.
39. Xue-Chun Yang,‡ Feng Wu,‡ Wen-Biao Wu,‡ X. Zhang and Jian-Jun Feng*
Enantioselective dearomative formal (3+3) cycloadditions of bicyclobutanes with aromatic azomethine imines: access to fused 2,3-diazabicyclo[3.1.1]heptanes
Chem. Sci., 2024, 15, 19488–19495
Highlighted in RSC英国皇家化学会
Enantioselective Dearomatizing Formal (3+3) Cycloadditions of Bicyclobutanes with Aromatic Azomethine Imines: Access to Fused 2,3-Diazabicyclo[3.1.1]heptanes
ChemRxiv 2024, DOI: 10.26434/chemrxiv-2024-zgffb, posted on Aug 06, 2024
Dedicated to Professor Yong Tang and Wanbin Zhang on the occasion of their 60th birthday
38. Feng Wu,‡ Wen-Biao Wu,‡ Y. Xiao, Z. Li, L. Tang, H.-X. He, X.-C. Yang, J.-J. Wang, Y. Cai, T.-T. Xu, J.-H. Tao,  G. Wang*  and Jian-Jun Feng*
Zinc-Catalyzed Enantioselective Formal (3+2) Cycloadditions of Bicyclobutanes with Imines: Catalytic Asymmetric Synthesis of Azabicyclo[2.1.1]hexanes
Angew. Chem. Int. Ed. 2024, e202406548
Highlighted in Synfacts 2024,20, 1208.
Highlighted in "化学深耕堂“ 、 and    X-Mol
37. Xin-Yu Gao, Lei Tang, Xu Zhang, Jian-Jun Feng*
Palladium‐catalyzed decarboxylative (4+3) cycloadditions of bicyclobutanes with 2‐alkylidenetrimethylene
carbonates for the synthesis of 2‐oxabicyclo[4.1.1]octanes.
Chem. Sci., 2024, 15, 13942-13948.  入选    Most popular 2024 organic chemistry articles
This article has been chosen for Prof Ning Jiao’s Editor’s Choice collection
Highlighted in “CBG 咨讯-人物与科研”  and
RSC英国皇家化学会
36. Xuan Zhan,‡ Heng-Xian He,‡ Quanxin Peng,‡ Jian-Jun Feng*
Synthesis of Cyclobutanes and Cyclobutenes by Strain-Release-Driven Ring-Opening of Bicyclo[1.1.0]butanes. (Invited review)
Synthesis 2024, 56, 3829-3848.
35.  Jian-Jun Feng*
Recent Progress in (3+3) Cycloadditions of Bicyclobutanes to Access Bicyclo[3.1.1]heptane Derivatives. (Invited review) Synpacts
Synlett 2025, 36, 621-629.
Invited by the Synlett & Synpact Editor, Prof. Ruben Martin, to further highlight our JACS paper in Synlett.
介绍该领域一般背景下研究小组在“热门”领域的贡献。
34. Y. Xiao, F. Wu, L. Tang, X. Zhang, M. Wei, G. Wang* and Jian-Jun Feng*
Dedicated to Professor Junliang Zhang on the occasion of his 50th birthday
Divergent Synthesis of Sulfur-Containing Bridged Cyclobutanes by Lewis Acid Catalyzed Formal Cycloadditions of Pyridinium 1,4-Zwitterionic Thiolates and Bicyclobutanes.
Angew. Chem. Int. Ed. 2024, 63, e202408578
Highlighted in "化学深耕堂“ 、“CBG 咨讯-人物与科研”    and    X-Mol
WileyChem
33. J.-L. Zhou,‡ Y. Xiao,‡ L. He, X.-Y. Gao, X.-C. Yang, W.-B. Wu, G. Wang, Junliang Zhang* and Jian-Jun Feng*
Palladium-Catalyzed Ligand-Controlled Switchable Hetero-(5+3)/Enantioselective [2σ+2σ] Cycloadditions of Bicyclobutanes with Vinyl Oxiranes.
J. Am. Chem. Soc. 2024, 146, 19621-19628.
Highlighted in 研之成理、“CBG 咨讯-人物与科研”and X-mol.       “化学深耕堂”
Highlighted in Synfacts 2024,20, 0820.
32. J.-J. Wang,‡ L. Tang,‡ Y. Xiao, W.-B. Wu，G. Wang* and Jian-Jun Feng*
Dedicated to Professor Yong Tang on the occasion of his 60th birthday
Switching between the [2π+2σ] and Hetero-[4π+2σ] Cycloaddition Reactivity of Bicyclobutanes with Lewis Acid Catalysts Enables the Synthesis of Spirocycles and Bridged Heterocycles.
Angew. Chem. Int. Ed. 2024, 63, e202405222
Highlighted in “CBG 咨讯-人物与科研”and "化学深耕堂“
and X-mol.\ WileyChem J.-J. Wang,‡ L. Tang,‡ Y. Xiao, W.-B. Wu and Jian-Jun Feng*
Lewis Acid Catalysis Enables Switch from [2π+2σ] to Hetero-[4π+2σ] Cycloaddition Reactivity of Bicyclo[1.1.0]butanes for Spiro- and Bridged-Heterocycle Synthesis
ChemRxiv 2024 DOI: 10.26434/chemrxiv-2024-r9c2g, Post on Mar 13, 2024
31. Y. Xiao,‡ T.-T. Xu,‡ J.-L. Zhou, F. Wu, L. Tang, R.-Y. Liu, W.-B. Wu,* and Jian-Jun Feng*
Photochemical α-selective radical ring-opening reactions of 1,3-disubstituted acyl bicyclobutanes with alkyl halides: modular access to the functionalized cyclobutenes.
Chem. Sci. 2023, 14, 13060–13066.
Highlighted in “CBG 咨讯-人物与科研”and "化学深耕堂“
and X-mol.
RSC英国皇家化学会
30. L. Tang,‡ Y. Xiao,‡ F. Wu, J.-L. Zhou, T.-T. Xu, and Jian-Jun Feng*
Silver-Catalyzed Dearomative [2π+2σ] Cycloadditions of Indoles with Bicyclobutanes: Access to Indoline Fused Bicyclo[2.1.1]hexanes.
Angew. Chem. Int. Ed. 2023, DOI: 10.1002/anie.202310066
ChemRxiv 2023, DOI:  10.26434/chemrxiv-2023-qkzmk, posted on July 11, 2023
Highlighted in “X-MOL” \ "化学深耕堂"\ WileyChem \ CBG咨询
化学空间
29. L. Tang,‡ Q.-N. Huang,‡ F. Wu, Y. Xiao,  J.-L. Zhou, T.-T. Xu, W.-B. Wu,* S. Qu,* and Jian-Jun Feng*
C(sp2)−H Cyclobutylation of hydroxyarenes enabled by silver-π-acid catalysis: diastereocontrolled synthesis of 1,3-difunctionalized cyclobutanes
Chem. Sci. 2023, 14, 9696–9703
Selected for the “2023 Chemical Science HOT Article Collection”
Accepted on 22 Aug 2023
ChemRxiv 2023, DOI:10.26434/chemrxiv-2023-cpq82, posted on June 26, 2023
Highlighted in “Mat+"
28. T.-T. Xu, Y. Xiao, J.-L. Zhou, L. Tang, F. Wu, J.-Y.-H. Sheng, W.-B. Wu,* and Jian-Jun Feng*
Boron Lewis Acid-Catalyzed Formal Insertion of Isocyanides into a C-O Bond of Benzyl Esters.
Org. Chem. Front., 2023,10, 4381-4387.
Highlighted in Frontiers Journals
27. Y. Xiao, L. Tang, T.-T. Xu, J.-Y.-H. Sheng, Z. Zhou, L. Yue, G. Wang,* M. Oestreich,* and Jian-Jun Feng*
Atom-Economic and Stereoselective Catalytic Synthesis of Fully Substituted Enol Esters/Carbonates of Amides in Acyclic Systems Enabled by Boron Lewis Acid Catalysis
Chem. Sci. 2023, 14, 5608-5618
Selected for the “2023 Chemical Science HOT Article Collection”
Highlighted in “CBG 咨讯-人物与科研”
26. Tong-Tong Xu, Jin-Lan Zhou, Guang-Yuan Cong, Jiang-Yi-Hui Sheng, Shi-Qi, Wang, Yating Ma, Jian-Jun Feng*
Boron Lewis Acid Catalysis Enables the Direct Cyanation of Benzyl Alcohols by Means of the Isonitrile as Cyanide Source
Molecules 2023, 28, 2174.
25. Yuanjiu Xiao,‡  Lei Tang,‡ Tong-Tong Xu, Jian-Jun Feng*
Boron Lewis Acid Catalyzed Intermolecular trans-Hydroarylation of Ynamides with Hydroxyarenes
Org. Lett. 2022, 24, 2619-2624.
24. Jian-Jun Feng*;‡ Mao, W.;‡ Zhang, L.;‡ Oestreich, M*.
Activation of the Si–B interelement bond related to catalysis.
Chem. Soc. Rev., 2021, 50, 2010-2073. (高被引论文)
柏林工业大学工作期间
23. Jian-Jun Feng;‡ Yan Xu;‡ Martin Oestreich*.
Chem. Sci. 2019, 10, 9679–9683.
Chosen as “ChemSci Pick of the Week”
Selected for the “2019 Chemical Science HOT Article Collection”
Highlighted in Nature Catalysis 2019, 2, 833.
Highlighted in Synfacts 2019, 15, 1402.
22. Jian-Jun Feng; Martin Oestreich*.
Tertiary α-Silyl Alcohols by Diastereoselective Coupling of 1,3-Dienes and Acylsilanes Initiated by Enantioselective Copper-Catalyzed Borylation
Angew. Chem. Int. Ed. 2019, 58, 8211–8215;
Highlighted in Synfacts 2019, 15, 889.
21. Jian-Jun Feng; Martin Oestreich*.
Copper-Catalyzed Silylation of C(sp3)−H Bonds Adjacent to Amide Nitrogen Atoms.
Org. Lett. 2018, 20, 4273−4276.
华东师范大学工作期间
20. Lin, T.-Y.; Wu, H.-H.; Feng, J.-J.*; Zhang, J.*
Chirality Transfer in Rhodium(I)-Catalyzed [3 + 2]-Cycloaddition of Vinyl Aziridines and Oxime Ethers: Atom-Economical Synthesis of Chiral Imidazolidines
Org. Lett. 2018, 20, 3587–3590.
19. Zhu, C.-Z.; Feng, J.-J.*; Zhang, J.*
Divergent synthesis of functionalized pyrrolidines and γ-amino ketones via rhodium-catalyzed switchable reactions of vinyl aziridines and silyl enol ethers
Chem. Commun., 2018, 54, 2401-2404.
18. Lin, T.-Y.; Wu, H.-H.; Feng, J.-J.*; Zhang, J.*
Divergent Access to Functionalized Pyrrolidines and Pyrrolines via Iridium-Catalyzed Domino-Ring-Opening Cyclization of Vinyl Aziridines with β-Ketocarbonyls
Org. Lett. 2017, 19, 6526−6529.
17. Lin, T.-Y.; Wu, H.-H.; Feng, J.-J.*;Zhang, J.*
Transfer of Chirality in the Rhodium-Catalyzed Chemoselective and Regioselective Allylic Alkylation of Hydroxyarenes with Vinyl Aziridines.
Org. Lett. 2017, 19, 2897–2900.
Highlighted in Synfacts 2017, 13, 846.
16. Zhu, C.-Z.; Feng, J.-J.*;Zhang, J.*
铑催化烯基氮杂环丙烷与炔胺的立体专一性[3＋2]环加成反应
Rhodium(I)-Catalyzed Stereospecific [3+2] Cycloadditions of Vinylaziridines and Ynamides.
Chin. J. Org. Chem. 2017, 37, 1165–1172.《有机化学》封面文章
15. Zhu, C.-Z.; Feng, J.-J.*;Zhang, J.*
Chem. Commun. 2017, 53, 4688–4691.
14. Lin, T.-Y.; Wu, H.-H.; Feng, J.-J.*; Zhang, J.*
ACS Catal. 2017, 7, 4047−4052.
13. Feng, J.-J.*; Zhang, J.*
Rhodium-Catalyzed Stereoselective Intramolecular Tandem Reaction of Vinyloxiranes with Alkynes: Atom- and Step-Economical Synthesis of Multifunctional Mono-, Bi-, and Tricyclic Compounds
ACS Catal. 2017, 7, 1533−1542.
12. Feng, J.-J.*; Zhang, J.*
Synthesis of Unsaturated N-Heterocycles by Cycloadditions of Aziridines and Alkynes
ACS Catal. 2016, 6, 6651−6661.  (Invited Perspectives)
11. Zhu, C.-Z.; Feng, J.-J.*;Zhang, J.*
Rhodium(I)-Catalyzed Intermolecular Aza-[4+3] Cycloaddition of Vinyl Aziridines and Dienes: Atom-Economical Synthesis of Enantiomerically Enriched Functionalized Azepines.
Angew. Chem. Int. Ed. 2017, 56, 1351–1355.
10. Lin, T.-Y.; Zhu, C.-Z.; Zhang, P.; Wang, Y.; Wu, H.-H.; Feng, J.-J.*;Zhang, J.*
Regiodivergent Intermolecular [3+2] Cycloadditions of Vinyl Aziridines and Allenes: Stereospecific Synthesis of Chiral Pyrrolidines.
Angew. Chem. Int. Ed. 2016, 55, 10844–10848.
9. Feng, J.-J.;‡ Lin, T.-Y.;‡ Zhu, C.-Z.; Wang, H.; Wu, H.-H.; Zhang, J.*.
The Divergent Synthesis of Nitrogen Heterocycles by Rhodium(I)-Catalyzed Intermolecular Cycloadditions of Vinyl Aziridines and Alkynes.
J. Am. Chem. Soc. 2016, 138, 2178–2181.
Highlighted in Synfacts 2016, 12, 491.
8. Feng, J.-J.; Lin, T.-Y.; Wu, H.-H.; Zhang, J.*
Modular Access to the Stereoisomers of Fused Bicyclic Azepines: Rhodium-Catalyzed Intramolecular Stereospecific Hetero-[5+2] Cycloaddition of Vinyl Aziridines and Alkenes.
Angew. Chem. Int. Ed. 2015, 54, 15854–15858.
7. Feng, J.-J.; Lin, T.-Y.; Wu, H.-H.; Zhang, J.*
Transfer of Chirality in the Rhodium-Catalyzed Intramolecular Formal Hetero-[5 + 2] Cycloaddition of Vinyl Aziridines and Alkynes: Stereoselective Synthesis of Fused Azepine Derivatives.
J. Am. Chem. Soc. 2015, 137, 3787−3790
研究生及本科学习期间
Publications before independent work:
06.  Chen, Y.-R.; Feng, J.-J.; Duan, W.-L.*  Tetrahedron Lett. 2014, 55, 595–597.
05.  Feng, J.-J.; Huang, M.; Lin, Z.-Q.; Duan, W.-L.*  Adv. Synth. Catal. 2012, 354, 3122–3126.
04.  Feng, J.-J.; Zhang, J.*
An Atom-Economic Synthesis of Bicyclo[3.1.0]hexanes by Rhodium N-Heterocyclic Carbene-Catalyzed Diastereoselective Tandem Hetero-[5 + 2] Cycloaddition/Claisen Rearrangement Reaction of Vinylic Oxiranes with Alkynes
J. Am. Chem. Soc. 2011, 133, 7304–7307.
03.  Feng, J.-J.; Chen, X.-F.; Shi, M.; Duan, W.-L.*
Palladium-Catalyzed Asymmetric Addition of Diarylphosphines to Enones toward the Synthesis of Chiral Phosphines.
J. Am. Chem. Soc. 2010, 132, 5562–5563.
02.  Shen, W.; Wang, L.-M.;* Feng, J.-J.; Tian, H.* Tetrahedron Lett. 2008, 49, 4047–4049.
01. Lin, B.-W.; Yin, S.-M.;* Feng, J.-J.; Ma, Y.-D. 青岛科技大学学报 2008, 29, 390–392.

段伟良, 冯见君, 一种高对映选择性催化合成手性膦化合物的方法, 申请日 2010.03.26; 申请号 201010133073.X; 授权公告日：2013-12-11；专利号： ZL201010133073.X.

2020：湖南大学高层次人才启动基金（已结题）
2017：德国“亚历山大·冯·洪堡基金会-洪堡学者”（已结题）

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