论文著作：
Yan-Mei Sun, Hai-Long Wu*, Jian-Yao Wang, Zhi Liu, Min Zhai, Ru-Qin Yu. Simultaneous determination of eight flavonoids in propolis using chemometrics-assisted high performance liquid chromatography-diode array detection. Journal of Chromatography B, 2014, 962： 59-67.
Chao Kang, Hai-Long Wu*, Li-Xia Xie, Shou-Xia Xiang, Ru-Qin Yu. Direct quantitative analysis of aromatic amino acids in human plasma by four-way calibration using intrinsic fluorescence: Exploration of third-order advantages. Talanta, 2014,122: 293-301.
Xiang-Dong Qing, Hai-Long Wu*, Xiu-Fang Yan, Yong Li, Li-Qun Ouyang, Chong-Chong Nie, Ru-Qin Yu. Development of a novel alternating quadrilinear decomposition algorithm for the kinetic analysis of four-way room-temperature phosphorescence data. Chemometrics and Intelligent Laboratory Systems, 2014, 132: 8-17.
Jian-Yao Wang, Hai-Long Wu*, Yan-Mei Sun, Hui-Wen Gu, Zhi Liu, Ya-Juan Liu and Ru-Qin Yu, Simultaneous determination of phenolic antioxidants in edible vegetable oils by HPLC-FLD assisted with second-order calibration based on ATLD algorithm, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2014, 947-948: 32-40.
Hai-Long Wu*, Yong Li, Ru-Qin Yu*. Developments of chemical multiway calibration methodologies possessing second-order or higher-order advantage, Journal of Chemometrics，2014, 28 (5): 476-489.
Xiu-Fang Yan, Hai-Long Wu, Xiang-Dong Qing, Yan-Mei Sun, Ru-Qin Yu. Interference-free determination of Indole-3-Acetic acid in two real systems using second-order calibration method coupled with excitation-emission matrix fluorescence. Analytical Sciences, 2014, 30 (4): 489-494.
ZHAI Min, WU HaiLong*, ZHANG ShuRong, ZHANG XiHua, SUN YanMei & YU RuQin. Interaction of epicatechin with bovine serum albumin using fluorescence quenching combined with chemometrics. SCIENCE CHINA -Chemistry, 2014, 57 (5): 748-754
Yong-Jie Yu,∗, Qiao-Ling Xia, Sheng Wang, Bing Wang, Fu-Wei Xie,Xiao-Bing Zhang, Yun-Ming Ma, Hai-Long Wu∗. Chemometric strategy for automatic chromatographic peak detection and background drift correction in chromatographic data. Journal of Chromatography A, 2014, 1359: 262–270.
Lu Xu, Si-Min Yan,Chen-Bo Cai,Xiao-Ping Yu, Jian-Hui Jiang, Hai-Long Wu, and Ru-Qin Yu.Nonlinear Multivariate Calibration of Shelf Life of Preserved Eggs (Pidan) by Near Infrared Spectroscopy: Stacked Least Squares Support Vector Machine with Ensemble Preprocessing. Journal of Spectroscopy, 2013, Article ID 797302, 7 pages. http://dx.doi.org/10.1155/2013/797302
Hui-Wen Gu, Hai-Long Wu,*, Xiao-Li Yin, Yong Li, Ya-Juan Liu, Hui Xia, Shu-Rong Zhang, Yi-Feng Jin, Xiao-Dong Sun, Ru-Qin Yu, Peng-Yuan Yang,**, Hao-Jie Lu. Multi-targeted interference-free determination of ten b-blockers in human urine and plasma samples by alternating trilinear decomposition algorithm-assisted liquid chromatography–mass spectrometry in full scan mode: Comparison with multiple reaction monitoring. Analytica Chimica Acta，2014，848: 10-24 (http://dx.doi.org /10.1016/j.aca. 2014.08. 052)
Xiao-Li Yin, Hai-Long Wu*, Hui-Wen Gu, Xiao-Hua Zhang, Yan-Mei Sun, Yong Hu, Lu Liu, Qi-Ming Rong, Ru-Qin Yu. Chemometrics-enhanced high performance liquid chromatography -diode array detection strategy for simultaneous determination of eight co-eluted compounds in ten kinds of Chinese teas using second-order calibration method based on alternating trilinear decomposition algorithm. Journal of Chromatography A, 2014, 1364:151-62.（doi: 10.1016/j.chroma.2014.08.068）。
Yong Li，Hai-Long Wu*，Xiao-Hua Zhang，Yao Chen，Hui-Wen Gu，Qi Zuo，Yan Zhang，Shan-Shan Guo，Xin-Yi Liu，Ru-Qin Yu. Estimating the chemical rank of three-way fluorescence data by vector subspace projection with Monte Carlo simulation. Chemometrics and Intelligent Laboratory Systems, 2014, 136: 15–23.
Yong Li, Hai-Long Wu, Chong-Chong Nie, Hui-Wen Gu, Xiang-dong Qing, Qi Zuo, Ru-qin Yu. Alternating coupled two-unequal residual functions algorithm for second-order calibration. Analytical Methods, 2014, Analytical Methods, 2014,6：6322-6331（DOI: 10.1039/C3AY42251H）
Kang Chao, Wu Hai-Long*, Xiang Shou-Xia, Xie Li-Xia, Liu Ya-Juan, Yu Yong-Jie, Sun Jing-Jing, Yu Ru-Qin. Simultaneous determination of aromatic amino acids in different systems using three-way calibration based on the PARAFAC-ALS algorithm coupled with EEM fluorescence: Exploration of second-order advantages. Analytical Methods, 2014, 6: 6358-6368
Shu-Rong Zhang, Hai-Long Wu,* Xi-Hua Zhang, Min Zhai, Ru-Qin Yu*. Quantitative study of state switching in proteins using a single probe combined with trilinear decomposition. New Journal of Chemistry, 2014, 38(6): 2422-2427. DOI: 10.1039/C3NJ01533E
Shu-Rong Zhang, Hai-Long Wu*, Ru-Qin Yu. A study on the differential strategy of some iterative trilinear decomposition algorithms: PARAFAC-ALS, ATLD, SWATLD, and APTLD, Journal of Chemometrics, 2015, 29(3): 179–192,
Xiang-Dong Qing, Hai-Long Wu *, Xi-Hua Zhang, Yong Li, Hui-Wen Gu, Ru-Qin Yu. A novel fourth-order calibration method based on alternating quinquelinear decomposition algorithm for processing high performance liquid chromatography–diode array detection-kinetic-pH data of naptalam hydrolysis. Analytica Chimica Acta, 2015, 861: 12-24.
Chao Kang, Hai-Long Wu*, Jing-Jing Song, Hui Xu, Ya-Juan Liu, Yong-Jie Yu, Xiao-Hua Zhang, Ru-Qin Yu. A flexible trilinear decomposition algorithm for three-way calibration based on the trilinear component model and a theoretical extension of the algorithm to the multilinear component model. Analytica Chimica Acta, 2015, 878: 63-77.
Hui-Wen Gu, Hai-Long Wu*, Xiao-Li Yin, Shan-Shan Li, Ya-Juan Liu, Hui Xia, Li-Xia Xie, Ru-Qin Yu, Peng-Yuan Yang**, Hao-Jie Lu. Solving signal instability to maintain the second-order advantage in the resolution and determination of multi-analytes in complex systems by modeling liquid chromatography–mass spectrometry data using alternating trilinear decomposition method assisted with piecewise direct standardization. Journal of Chromatography A, 2015, 1407: 157-168.
Xiao-Li Yin, Hai-Long Wu*, Hui-Wen Gu, Yong Hu, Hui Xia, Li Wang, Ru-Qin Yu. Second-order calibration method applied to process three-way excitation-emission-kinetic fluorescence data: A novel tool for real-time quantitative analysis of the lactone hydrolysis of irinotecan in human plasma. Chemometrics and Intelligent Laboratory Systems, 2015, 146: 447-456.
Yong Hu, Hai-Long Wu*, Xiao-Li Yin, Hui-Wen Gu, Chao Kang, Shou-Xia Xiang, Hui Xia, Ru-Qin Yu. Chemometrics-assisted determination of amiloride and triamterene in biological fluids with overlapped peaks and unknown interferences. Bioanalysis, 2015, 7(13): 1685-1697.
Li-Xia Xie, Hai-Long Wu,* Chao Kang, Shou-Xia Xiang, Xiao-Li Yin, Hui-Wen Gu, Qi Zuo and Ru-Qin Yu. Quantitative investigation of the dynamic interaction of human serum albumin with procaine using a multi-way calibration method coupled with three-dimensional fluorescence spectroscopy. Analytical Methods, 2015, 7: 6552-6560.
Shou-Xia Xiang, Hai-Long Wu*, Chao Kang, Li-Xia Xie, Xiao-Li Yin, Hui-Wen Gu, Ru-Qin Yu. Fast quantitative analysis of four tyrosine kinase inhibitors in different human plasma samples using three-way calibration assisted liquid chromatography with diode array detection. Journal of Separation Science, 2015, 38: 2781-2788.
Yong-Jie Yu, Hai-Yan Fu, Hui-Wen Gu, Yong Li, Chao Kang, Yi-Peng Wang, Hai-Long Wu*. Chemical rank estimation for second-order calibration by discrete Fourier transform coupled with robust statistical analysis. Chemometrics and Intelligent Laboratory Systems, 2015, 141: 47-57
Yan Zhang, Lijuan Tang, Hongyan Zou, Qin Yang, Xinliang Yu, Jianhui Jiang, Hailong Wu, Ruqin Yu. Identifying protein arginine methylation sites using global features of protein sequence coupled with support vector machine optimized by particle swarm optimization algorithm. Chemometrics and Intelligent Laboratory Systems, 2015, 146:102-107.
Hui Xia, Hai-Long Wu*, Hui-Wen Gu, Xiao-Li Yin, Huan Fang, Ru-Qin Yu. Simultaneous determination of naphazoline and pyridoxine in eye drops using excitation–emission matrix fluorescence coupled with second-order calibration method based on alternating trilinear decomposition algorithm. Chinese Chemical Letters, 2015, 26(12): 1446-1449.
吴海龙 撰稿, 创新化学为学界楷模 通晓育人具大师风范—庆贺我国著名分析化学家俞汝勤院士八秩华诞, 分析化学, 2015, 43(11): 1607-1611.
吴海龙*,李勇,康超,俞汝勤. 三维荧光化学多维校正方法研究新进展. 分析化学, 2015, 43(11): 1629-1637.
Liu, Zhi; Wu, Hai-Long; Li, Yong; Gu, Hui-Wen; Yin, Xiao-Li; Xie, Li-Xia; Yu, Ru-Qin. Rapid and simultaneous determination of five vinca alkaloids in Catharanthus roseus and human serum using trilinear component modeling of liquid chromatography-diode array detection data, Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 1026:114-123.
Zhang, Xiao-Hua; Wu, Hai-Long; Yin, Xiao-Li; Li, Yong; Qing, Xiang-Dong; Gu, Hui-Wen; Kang, Chao; Yu, Ru-Qin. Exploiting third-order advantage using four-way calibration method for direct quantitative analysis of active ingredients of Schisandra chinensis in DMEM by processing four-way excitation-emission-solvent fluorescence data, Chemometrics and Intelligent Laboratory Systems, 155: 46-53, 2016/7/15.
Gu, Hui-Wen; Wu, Hai-Long; Li, Shan-Shan; Yin, Xiao-Li; Hu, Yong; Xia, Hui; Fang, Huan; Yu, Ru-Qin; Yang, Peng-Yuan; Lu, Hao-Jie. Chemometrics-enhanced full scan mode of liquid chromatography-mass spectrometry for the simultaneous determination of six co-eluted sulfonylurea-type oral antidiabetic agents in complex samples, Chemometrics and Intelligent Laboratory Systems, 155:62-72, 2016/7/15.
Fu, Haiyan; Li, Hedong; Shao, Mei; Yang, Tianming; Zhang, Xu; Xu, Rujing; Wei, Yujuan; Chen, Shuhua; Ni, Chuang; Wu, Hailong, Simultaneous determination of Repaglinide and Irbesartan in biological plasmas using micellar enhanced excitation-emission matrix fluorescence coupled with ATLD method, Science China -Chemistry, 59(7): 816-823, 2016/7.
Chao Kang; Hai-Long Wu; Chang Zhou; Shou-Xia Xiang; Xiao-Hua Zhang; Yong-Jie Yu; Ru-Qin Yu, Quantitative fluorescence kinetic analysis of NADH and FAD in human plasma using three- and four-way calibration methods capable of providing the second-order advantage, Analytica Chimica Acta, 910:36-44, 2016/3/3.
Yin, Xiao-Li; Wu, Hai-Long; Gu, Hui-Wen; Hu, Yong; Wang, Li; Xia, Hui; Xiang, Shou-Xia; Yu, Ru-Qin. Chemometrics-assisted high performance liquid chromatography-diode array detection strategy to solve varying interfering patterns from different chromatographic columns and sample matrices for beverage analysis, Journal of Chromatography A, 1435:75-84, 2016/2/26.
Yan Zhang; Hong-Yan Zou; Pei Shi; Qin Yang; Li-Juan Tang; Jian-Hui Jiang; Hai-Long Wu; Ru-Qin Yu. Determination of benzo[a]pyrene in cigarette mainstream smoke by using mid-infrared spectroscopy associated with a novel chemometric algorithm, Analytica Chimica Acta, 902: 43-49, 2016/1/1.
Zhu, Li; Wu, Hai-Long; Xie, Li-Xia; Fang, Huan; Xiang, Shou-Xia; Hu, Yong; Liu, Zhi; Wang, Tong; Yu, Ru-Qin. A chemometrics-assisted excitation-emission matrix fluorescence method for simultaneous determination of arbutin and hydroquinone in cosmetic products, Analytical Methods,2016, 8(24):4941-4948 .
Liu, Zhi; Wu, Hai-Long; Gu, Hui-Wen; Yin, Xiao-Li; Xie, Li-Xia; Hu, Yong; Xia, Hui; Xiang, Shou-Xia; Yu, Ru-Qin. Interference-free analysis of aflatoxin B-1 and G(1) in various foodstuffs using trilinear component modeling of excitation-emission matrix fluorescence data enhanced through photochemical derivatization, RSC Advances,2016, 6(31):25850-25863, .
Li-Xia Xie, Hai-Long Wu*, Yu Fang, Chao Kang, Shou-Xia Xiang, Li Zhu, Xiao-Li Yin, Hui-Wen Gu, Zhi Liu, Ru-Qin Yu. Simultaneous determination of tyrosine and levodopa in human plasma using enzyme-induced excitation-emission-kinetic third-order calibration method. Chemometrics and Intelligent Laboratory Systems, 2016,148:9-19
卿湘东, 吴海龙, 张喜华, 李勇, 谷惠文, 文瑾, 申湘忠, 俞汝勤. 交替加权四线性分解算法用于处理非五线性五维数阵. 中国科学: 化学，2016, 46(4): 401-408； Xiang-Dong Qing, Hai-Long Wu*, Xi-Hua Zhang, Yong Li, Hui-Wen Gu, Jin Wen, Xiang-Zhong Shen, Ru-Qin Yu. A new alternating weighted quadrilinear decomposition algorithm with application for analysis of non-quinquelinear five-way data arrays. Scientia Sinica Chimica, 2016, 46(4): 401-408
卿湘东,吴海龙*,谷惠文,尹小丽,文瑾,申湘忠,俞汝勤. 三线性分解方法用于光谱数据中背景漂移的扣除.化学学报， 2016， 74（3）：277-284（DOI: 10.6023/A15110704）； Xiang-Dong Qing, Hai-Long Wu*, Hui-Wen Gu, Xiao-Li Yin, Jin Wen, Xiang-Zhong Shen, Ru-Qin Yu. Removal of background drift nonlinear interference in 3-D spectral arrays for multi-way calibration using trilinear decomposition methods. Acta Chimica Sinica, 2016, 74(3): 277-284
Ya-Juan Liu; J. Jansen; G. Postma; T. Tran; Hai-Long Wu; L.M.C. Buydens. Angle distribution of loading subspaces (ADLS) for chemical rank estimation in three-way analysis. Chemometrics and Intelligent Laboratory Systems, 2016,152：146-156.
Li Wang, Hai-Long Wu*, Xiao-Li Yin, Yong Hu, Hui-Wen Gu, Ru-Qin Yu. Simultaneous determination of umbelliferone and scopoletin in Tibetan medicine Saussurea laniceps and traditional Chinese medicine Radix angelicae pubescentis using excitation-emission matrix fluorescence coupled with second-order calibration method. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy，2017,170:104–110
Xie, L.-X., Wu, H.-L., Zhang, X.-H., Wang, T., Zhu, L., Xiang, S.-X., Liu, Z., Yu, R.-Q.“Slicing” data array in quadrilinear component model: An alternative quadrilinear decomposition algorithm for third-order calibration method(2017) Chemometrics and Intelligent Laboratory Systems, 167:12-22.
Liu, Z., Wu, H.-L., Xie, L.-X., Hu, Y., Fang, H., Sun, X.-D., Wang, T., Xiao, R., Yu, R.-Q.Direct and interference-free determination of thirteen phenolic compounds in red wines using a chemometrics-assisted HPLC-DAD strategy for authentication of vintage year. Analytical Methods, 2017，9 (22): 3361-3374.
Tong Wang, Hai‐Long Wu, Li‐Xia Xie, Li Zhu, Zhi Liu, Xiao‐Dong Sun, Rong Xiao, Ru‐Qin Yu.Fast and simultaneous determination of 12 polyphenols in apple peel and pulp by using chemometrics‐assisted high‐performance liquid chromatography with diode array detection. Journal of Separation Science, 2017， 40( 8): 1651-1659.
Hu, Y., Wu, H.-L., Yin, X.-L., Gu, H.-W., Xiao, R., Wang, L., Fang, H., Yu, R.-Q.Interference-free spectrofluorometric quantification of aristolochic acid I and aristololactam I in five Chinese herbal medicines using chemical derivatization enhancement and second-order calibration methods(2017) Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 175:229-238.
Liu, Z., Wu, H.-L., Xie, L.-X., Hu, Y., Fang, H., Sun, X.-D., Wang, T., Xiao, R., Yu, R.-Q. Chemometrics-enhanced liquid chromatography-full scan-mass spectrometry for interference-free analysis of multi-class mycotoxins in complex cereal samples (2017) Chemometrics and Intelligent Laboratory Systems, 160:125-138.
Xiao, R., Wu, H.-L., Hu, Y., Yin, X.-L., Gu, H.-W., Liu, Z., Wang, T., Sun, X.-D., Yu, R.-Q.Simultaneous determination of warfarin and aspirin contents in biological fluids using excitation-emission matrix fluorescence coupled with a second-order calibration method. Analytical Sciences, 2017，33 (1): 29-34.
Yong Li, Hai-long Wu* , Xiang-yang Yu, Dealing with three-way data containing missing values by new weighted method for second-order calibration. Chemometrics and Intelligent Laboratory Systems,2017, 171: 207–217
Xiao-Li Yin, Hui-Wen Gu*, Xiao-Lu Liu, Shan-Hui Zhang, Hai-Long Wu*. Comparison of three-way and four-way calibration for the real-time quantitative analysis of drug hydrolysis in complex dynamic samples by excitation-emission matrix fluorescence. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018,192: 437-445
Yong Hu, Hai-Long Wu*, Xiao-Li Yin, Hui-Wen Gu, Rong Xiao, Li-Xia Xie, Zhi Liu, Huan Fang,Li Wang, Ru-Qin Yu. Rapid and interference-free analysis of nine B-group vitamins in energy drinks using trilinear component modeling of liquid chromatography-mass spectrometry data.Talanta, 2018,180:108-119.
Yong Hu, Hai-Long Wu*, Xiao-Li Yin, Hui-Wen Gu, Zhi Liu, Rong Xiao, Li-Xia Xie, Huan Fang, Ru-Qin Yu, A flexible and novel strategy of alternating trilinear decomposition method coupled with two-dimensional linear discriminant analysis for three-way chemical data analysis: Characterization and classification. Analytica Chimica Acta,2018,1021:28-40
Yue-Yue Chang, Hai-Long Wu*, Huan Fang, Tong Wang, Ru-Qin Yu. Rapid, simultaneous and interference-free determination of three rhodamine dyes illegally added into chilli samples using excitation-emission matrix fluorescence coupled with second-order calibration method. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018, 204:141-149.
Wan‐Jun Long, Hai‐Long Wu*, Tong Wang, Li‐Xia Xie, Yong Hu, Huan Fang, Li Cheng, Yu‐Jie Ding, Ru‐Qin Yu. Chemometrics‐assisted liquid chromatography with full scan mass spectrometry for the interference‐free determination of glucocorticoids illegally added to face masks. Journal of Separation Science|, 2018, 41(18): 3527-3537.
Yong Li, Hui-Wen Gu, Hai-Long Wu*, Xiang-Yang Yu. Comparison of the performances of several commonly used algorithms for second-order calibration. ANALYTICAL METHODS. 2018,10 (39): 4801-4812 , DOI: 10.1039/c8ay01443d
Yong Li, Hai-long Wu*, Xiang-yang Yu. Dealing with three-way data containing missing values by new weighted method for second-order calibration. Chemometrics and Intelligent Laboratory Systems, 2017, 171: 207-217。
Tong Wang, Hai-Long Wu*, Li-Xia Xie, Zhi Liu, Wan-Jun Long, Li Cheng, Yu-Jie Ding, Ru-Qin Yu*. Simultaneous and interference-free determination of eleven non-steroidal anti-inflammatory drugs illegally added into Chinese patent drugs using chemometrics-assisted HPLC-DAD strategy. SCIENCE CHINA-CHEMISTRY. 2018, 61(6): 739-749。
Yong Hu, Hai-Long Wu*, Xiao-Li Yin, Hui-Wen Rong Xiao, Li-Xia Xie, Zhi Liu, Huan Fang, Li Wang, Ru-Qin Yu. Rapid and interference-free analysis of nine B-group vitamins in energy drinks using trilinear component modeling of liquid chromatography-mass spectrometry data. TALANTA 2018, 180: 108-119.
Xiao-Dong Sun,Hai-Long Wu*， Zhi Liu, Li-Xia Xie, Yong Hu, Huan Fang, Tong Wang, Rong Xiao, Yu-Jie Ding, Ru-Qin Yu. Chemometrics-assisted liquid chromatography-full scan mass spectrometry for simultaneous determination of multi-class estrogens in infant milk powder. ANALYTICAL METHODS. 2018, 10(12): 1459-1471
Qian Liu , Hai-Long Wu*, Zhi Liu, Rong Xiao, Tong Wang, Yong Hu, Yu-Jie Ding, Ru-Qin Yu. Chemometrics-assisted HPLC-DAD as a rapid and interference-free strategy for simultaneous determination of 17 polyphenols in raw propolis. ANALYTICAL METHODS. 2018, 10 (46): 5577-5588; DOI: 10.1039/ c8ay01986j
Ya-Juan Liu, Geert Postma, Hai-Long Wu, Hui-Wen Gu, Ludovic Duponchel. Angle Distribution of Loading Subspace (ADLS) for estimating chemical rank in multivariate analysis: Applications in spectroscopy and chromatography. Talanta, 2019,194:90-97.
Xiao-Hua Zhang, Xiang-Dong Qing, Hai-Long Wu.Discussion on the superiority of third-order advantage: Analytical application for four-way data in complex system, Microchemical Journal, 2019, 145: 1078- 1085.
Chao Kang, Hai-Long Wu*, Min-Li Xu, Xiu-Fang Yan, Ru-Qin Yu. Simultaneously quantifying intracellular FAD and FMN using a novel strategy of intrinsic fluorescence four-way calibration. Talanta, 2019, 197: 105-112
Tong Wang, Hai-Long Wu*, Li-Xia Xie, Wan-Jun Long, Ru-Qin Yu*. A novel quadrilinear decomposition method for four-way data arrays analysis based on algorithms combination strategy: Comparison and application. Chemometrics and Intelligent Laboratory Systems, 2019, In press.
吴海龙
湖南省
研究领域：
环保,新材料,石油炼制,石油化工,精细化工,生物医药
研究方向：
1) 化学传感器，流动注射分析，HPLC-DAD，三维荧光光谱，LC-MS，生化分析，环境监测，药物分析，食品安全分析等；
2) 化学计量学，稳健统计学，对应分析，三维数阵分析，多元校正，二阶校正，二阶标准加入法、多线性分解、化学多维校正等；
3) 多维数阵分析及多维校正新应用：生命科学、环境科学、药学、医学、食品科学等；
4）蛋白质定量分析、代谢组学、药代动力学等；
5) 自动化和控制系统中的多维数阵分析。
所在单位：
湖南大学
