精细化工

1. 仿生催化——不饱和小分子活化和惰性C-H键活化
2. 生物无机化学——血红素结构和功能的模拟
3. 超分子化学——共价有机框架（COF）材料的设计与合成

(1)     Borong Liao, Junhao Gao, Pei Weng, Linya He, Yusheng Zhang,* Qiuhua Liu,* Zaichun Zhou,* Semiconductor Effectfrom Pd(II) Porphyrin Metal to Its Ligand in Photocatalytic N-Dealkylation, ChemSusChem, 2025, 18, e202401381.
(2)     Qiuhua Liu*, Junhao Gao, Qin Lin, Borong Liao, Qian Zhang, Zaichun Zhou*, Size- and Charge-Matching Effect Between Porphyrin Core and Central Metal on the Stability of Cuprous Ion, Appl. Organomet. Chem., 2024, 38(1): e7318.
(3)     Qiuhua Liu, Chongchen Xiang, Qingxing Wu, Zaichun Zhou*, Yingping Zou, Wanqiang Liu*, Theoretical Exploration of the Molecular Stacking and Charge Transfer Mechanism of PBQx:Y6 OSCs, Surf. Interfaces, 2024, 44(1): 103767.
(4)     Qiuhua Liu*, Junhao Gao, Yusheng Zhang, Xin Liu, Xi Zhang, Qin Lin, Wennan Zeng, Zaichun Zhou*, A trans-ortho Asymmetrically di-Strapped Metalloporphyrin Integrating Three Key Structural Features of Ligand In Heme, Chinese Chem. Lett., 2023, 34(10): 108315.
(5)     Qiuhua Liu, Wanjie Ren, Siwei Zhang, Yang Huang, Dilong Chen, Wennan Zeng, Zaichun Zhou*, Lin He*, Wenping Guo*, Jianfeng Li*, d-Orbital Reconstructions Forced by Double Bow-Shaped Deformations and Second Coordination Sphere Effects of Cu(II) Heme Analogs in HER, Chem. Eur. J., 2022, 28(8): e202103892.
(6)     Qiuhua Liu*, Xiaorong Shen, Ye Dai, Mengchen Zhang, Zaichun Zhou*, Porous Materials Formed by Four Self-Construction Processes, Org. Biomol. Chem., 2022, 20(41): 8149–8156.
(7)     Jinjin Zhang, Min Tang, Dilong Chen, Binghua Lin, Zaichun Zhou*, Qiuhua Liu*, Horizontal and Vertical Push Effects in Saddled Zinc Porphyrin Complexes: Implications for Heme Distortion, Inorg. Chem., 2019, 58(4): 2627–2636.
(8)     Brian Pattengale, Qiuhua Liu, Wenhui Hu, Sizhuo Yang, Peilei He, Sir Lawrence Tender, Yingqi Wang, Xiaoyi Zhang, Zaichun Zhou*, Jian Zhang*, Jier Huang*, Selective Excited State Dynamics in a Unique Set of Rationally Designed Ni Porphyrins, J. Phys. Chem. C, 2019, 123(29): 17994–18000.
(9)     Min Tang, Yan Yang, Shaowei Zhang, Jiafu Chen, Jian Zhang, Zaichun Zhou*, Qiuhua Liu*, Electron Transfer and Geometric Conversion of Co−NO Moiety in Saddled Porphyrins: Implications for Trigger Role of Tetrapyrrole Distortion, Inorg. Chem., 2018, 57(1): 277–287.
(10)  Qiuhua Liu, Jinjin Zhang, Min Tang, Yan Yang, Jian Zhang*, Zaichun Zhou*, Geometric Deconstruction of Core and Electron Activation of a π-System in a Series of Deformed Porphyrins: Mimics of Heme, Org. Biomol. Chem., 2018, 16(41): 7725–7736.
(11) Min Tang, Yan Yang, Shaowei Zhang, Jiafu Chen, Jian Zhang, Zaichun Zhou,* Qiuhua Liu,* Electron Transfer and Geometric Conversion of Co−NO Moiety in Saddled Porphyrins: Implications for Trigger Role of Tetrapyrrole Distortion, Inorg. Chem., 2018, 57(1): 277–287.
(12) Zaichun Zhou,* Xiaochun Zhou, Qiuhua Liu,* Xi Zhang, Haomin Liu, Fixation of Zinc(II) Ion to Dioxygen in a Highly Deformed Porphyrin: Implications for the Oxygen Carrier Mechanism of Distorted Heme, Org. Lett., 2015, 17(16): 4078–4081.
(13) Qiuhua Liu, Xi Zhang, Wennan Zeng, Jianxiu Wang,* Zaichun Zhou,* Fine-Tuning of Electronic Structure of Cobalt(II) Ion in Nonplanar Porphyrins and Tracking of a Cross-hybrid Stage: Implications for the Distortion of Natural Tetrapyrrole Macrocycles, J. Phys. Chem. B,2015, 119(44): 14102–14110.
(14) Qiuhua Liu, Xiaochun Zhou, Haomin Liu, Xi Zhang, Zaichun Zhou,*Fractional Transfer of a Free Unpaired Electron to Overcome Energy Barriers in the Formation of Fe4+ from Fe3+ during Core Contraction of Macrocycles: Implication for Heme Distortion, Org. Biomol. Chem., 2015, 13(10): 2939–2946.
(15) Zaichun Zhou,* Xi Zhang, Qiuhua Liu,* Ziqiang Yan, Chengjin Lv,Ge Long, Geometry and Temperature Dependence of meso-Aryl Rotation in Strained Metalloporphyrins: Adjustable Turnstile Molecules, Inorg. Chem., 2013, 52(18): 10258–10263.
(16) Zaichun Zhou,* Qiuhua Liu, Ziqiang Yan, Ge Long, Xi Zhang, Chenzhong Cao,* Rongqing Jiang, Conversion of Electron Configuration of Iron Ion through Core Contraction of Porphyrin: Implications for Heme Distortion, Org. Lett., 2013, 15(3): 606–609.
(17) Zaichun Zhou,* Min Shen, Chenzhong Cao, Qiuhua Liu, Ziqiang Yan, The Opposing Influences of Ruffling and Doming Deformation on the 4-N Cavity Size of Porphyrin Macorcycles: the Role of Heme Deformations Revealed, Chem. Eur. J., 2012, 18(25): 7675–7679.
(18) Yinchun Jiao, ChenzhongCao,* Zaichun Zhou, Direct Synthesis of anti-1,3-Diols through Nonclassical Reaction of Aryl Grignard Reagents with Isopropenyl Acetate, Org. Lett., 2011, 13(2): 180–183.
(19) Zaichun Zhou, Chenzhong Cao,* Qiuhua Liu, Rongqing Jiang, Hybrid Orbital Deformation (HOD) Effect and Spectral Red-Shift Property of Nonplanar porphyrin, Org. Lett., 2010, 12(8):1780–1783.
(20) Zaichun Zhou, Chenzhong Cao,* Zhiqing Yin, Qiuhua Liu, Bis(zinc porphyrin) Bridged by Benzo Orthocarbonates as a Conformational Switch under Regulation of DABCO and a Cu+ Ion, Org. Lett., 2009, 11(8):1781–1784.

(1) 周再春、张梦臣、张金金、刘秋华，一类基于环聚物折叠和组装的框架分子及其制备方法，中国专利，ZL 2018115995190，2021年12月03日授权。
(2) 周再春、陈地龙、刘秋华，2,2',6,6'-四羧基-[4,4'-联吡啶]的合成方法，中国专利，ZL 2018115995063，2021年10月08日授权。
(3) 刘秋华、雷行、周再春、陈地龙、林炳华，一种铜卟啉催化剂及其复合材料的制备及应用，中国专利，ZL 202010556636X，2021年08月31日授权。
(4) Qiuhua Liu, Huiyang Xu, Zaichun Zhou, Siwei Zhang, Heme Ligand Mimetics and Synthesis Method, 澳大利亚革新专利, 2020103151，2020年12月30日授权。

1.血红素中Fe-O2络合的顺磁性依赖（No. 201372069），国家自然科学基金面上项目，2014.01—2017.12
2.扭曲度可调型类血红素铁卟啉的合成及其复合物性能研究（No. 21071051），国家自然科学基金面上项目，2011.01—2013.12
3.非平面铁卟啉的合成及其催化氧化性能研究（No. 211121），教育部科学研究重点项目，2011.08—2013.12

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