新材料,石油炼制,石油化工,精细化工,生物医药

生物无机化学和金属化学生物学

Photodynamic Therapy;Apoptosis;Antitumor Agents;Ruthenium;G-quadruplexes;Hydrolysis;Crystal Structure;Cyclodextrins;Sirna;Quantum Dots

1、“金属酶的化学模拟及其构效关系研究”获2012年国家自然科学二等奖（第一完成人）
2、“新时期化学创新人才培养模式的探索与实践”获2018年国家教学成果二等奖（第一完成人）

论文：
1. Y.-Y. Lin#, X.-Y. Xia#, L. Hao, W.-J. Wang, H. Zhang, L.-Y. Liu, W. Liu, Z.-Y. Li, C.-P. Tan*, Z.-W. Mao*, Simultaneous Photoactivation of cGAS-STING Pathway and Pyroptosis by Pt(II)-Triphenylamine Complexes for Cancer Immunotherapy. Angew. Chem. Int. Ed. 2022. e202210988.
2. K.-N. Wang, L.-Y. Liu, D. Mao, M.-X. Hou, C.-P. Tan, Z.-W. Mao*, B. Liu*, A Nuclear-Targeted AIE Photosensitizer for Enzyme Inhibition and Photosensitization in Cancer Cell Ablation. Angew. Chem. Int. Ed. 2022, 61(15), e202114600. 
3. L.-Y. Liu, T.-Z. Ma, Y.-L. Zeng, W. Liu*, Z.-W. Mao*, Structural Basis of Pyridostatin and Its Derivatives Specifically Binding to G-Quadruplexes. J. Am. Chem. Soc. 2022, 144(26), 11878-11887. 
4. W. Liu, B.-C. Zhu, L.-Y. Liu, X.-Y. Xia, Z.-W. Mao*, G-quadruplex structural transition driven by a platinum compound. Nucleic Acids Res. 2022, 50(14), 7816-7828. 
5. W.-J. Wang#, Y.-Y. Ling#, Y.-M. Zhong, Z.-Y. Li, C.-P. Tan* , Z.-W. Mao*, Ferroptosis-Enhanced Cancer Immunity by a Ferrocene-Appended Iridium(III) Diphosphine Complex. Angew. Chem. Int. Ed. 2022, 61(16), e202115247.
6. Z. Zhao, X. Tao, Y. Xie, Q. Lai, W. Lin, K. Lu, J. Wang, W. Xia*, Z.-W. Mao*, In Situ Prodrug Activation by an Affibody-Ruthenium Catalyst Hybrid for HER2-Targeted Chemotherapy. Angew. Chem. Int. Ed. 2022, 61(26), e202202855. 
7. X. Su, W.-J. Wang, Q. Cao*, H. Zhang, B. Liu, Y. Ling, X. Zhou, Z.-W. Mao*, A Carbonic Anhydrase IX (CAIX)-Anchored Rhenium(I) Photosensitizer Evokes Pyroptosis for Enhanced Anti-Tumor Immunity. Angew. Chem. Int. Ed. 2022, 61(8), e202115800.
8. L. Hao, Y.-Y. Ling, Z.-X. Huang, Z.-Y. Pan, C.-P. Tan*, Z.-W. Mao*, Real-Time Tracking of ER Turnover during ERLAD by a Rhenium Complex via Lifetime Imaging. Natl. Sci. Rev. 2022, 9, nwab194.
9. K. Peng, B.-B. Liang, W. Liu, Z.-W. Mao*, What blocks more anticancer platinum complexes from experiment to Clinic: Major Problems and Potential Strategies from Drug Design Perspectives. Coord. Chem. Rev., 2021, 449, 214210. 
10. W.-J. Wang#, M. Xia#, C.-P. Tan*, Y.-J. Wang, Y.-B. Zhang*, G.-H. Li*, Z.-W. Mao*, Induction and Monitoring of DNA Phase Separation in Living Cells by a Light-Switching Ruthenium Complex. J. Am. Chem. Soc. 2021, 143(30), 11370-11381. 
11. L.-Y. Liu, K.-N. Wang, W. Liu*, Y.-L. Zeng, M.-X. Hou, J. Yang, Z.-W. Mao*, Spatial Matching Selectivity and Solution Structure of Organic-Metal Hybrid to Quadruplex-Duplex Hybrid. Angew. Chem. Int. Ed. 2021, 60(38), 20833-20839. 
12. F.-X. Wang#, J.-W. Liu#, X.-Q. Hong#, C.-P. Tan#, L. Zhang*, W.-H. Chen*, P. Sadler*, Z.-W. Mao*, Anion-Responsive Manganese Porphyrin Facilitates Chloride Transport and Induces Immunogenic Cell Death. CCS Chem. 2021, 3, 2527-2537.
13. K.-N. Wang#, X. Shao#, Z. Tian#, L.-Y. Liu#, C. Zhang#, C.-P. Tan, J. Zhang, P. Ling, F. Liu, Q. Chen*, J. Diao*, Z.-W. Mao*, A Continuous Add-On Probe Reveals the Nonlinear Enlargement of Mitochondria in Light-Activated Oncosis. Adv. Sci. 2021, 8(17), 2004566. DOI: 10.1002/advs.202004566.
14. B.-C. Zhu, J. He, W. Liu*, X.-Y. Xia, L.-Y. Liu, B.-B. Liang, H.-G. Yao, B. Liu, L.-N. Ji, Z.-W. Mao*, Selectivity and Targeting of G-quadruplex Binders Activated by Adaptive Binding and Controlled by Chemical Kinetics. Angew. Chem. Int. Ed. 2021, 60(28), 15340-15343. 
15. K.-N. Wang#, L.-Y. Liu#, D. Mao, S. Xu, C.-P. Tan, Q. Cao, Z.-W. Mao*, B. Liu*, A Polarity-Sensitive Ratiometric Fluorescence Probe for Monitoring Changes in Lipid Droplets and Nucleus during Ferroptosis. Angew. Chem. Int. Ed. 2021, 60(27), 15095-15100. 
16. K.-N. Wang#, L.-Y. Liu#, G. Qi, X.-J. Chao, W. Ma, Z. Yu*, Q. Pan, Z.-W. Mao*, B. Liu*, Light-Driven Cascade Mitochondria-to-Nucleus Photosensitization in Cancer Cell Ablation. Adv. Sci. 2021, 8(8), 2004379. 
17. Q. Cao#, D.-J. Zhou#, Z.-Y. Pan#, G.-G. Yang, H. Zhang, L.-N. Ji, Z.-W. Mao*, CAIXplatins: Highly Potent Platinum(IV) Prodrugs Selective Against Carbonic Anhydrase IX for the Treatment of Hypoxic Tumors. Angew. Chem. Int. Ed. 2020, 59(42), 18556-18562.
18. L.-Y. Liu #, H. Fang#, Q. Chen#, M. H.-Y. Chan#, M. Ng, K.-N. Wang, W. Liu, Z. Tian, J. Diao*, Z.-W. Mao*, V. W.-W. Yam*, Multiple-Color Platinum Complex with Super-Large Stokes Shift for Super-Resolution Imaging of Autolysosome Escape. Angew. Chem. Int. Ed. 2020, 59(43), 19229-19236. 
19. Z.-Y. Pan, C.-P. Tan*, L.-S. Rao, H. Zhang, Y. Zheng, L. Hao, L.-N. Ji, Z.-W. Mao*, Recoding the Cancer Epigenome by Intervening in Metabolism and Iron Homeostasis with Mitochondria-Targeted Rhenium(I) Complexes. Angew. Chem. Int. Ed. 2020, 59(42), 18755-18762. 
20. L.-Y. Liu#, W. Liu#, K.-N. Wang, B.-C. Zhu, X.-Y. Xia, L.-N. Ji, Z.-W. Mao*, Quantitative Detection of G-Quadruplex DNA in Live Cells Based on Photon Counts and Complex Structure Discrimination. Angew. Chem. Int. Ed. 2020, 59(24), 9719-9726.

K. Lu, B. Luo, X. Tao, Y. Luo, M. Ao, B. Zheng, X. Xu, X. Ma, J. Niu, H. Li, Y. Xie, Z. Zhao, P. Zheng, G. Wang, S. Gao, C. Wang, W. Xia*, Z. Su*, Z.-W. Mao*. Complex structure and activation mechanism of arginine kinase McsB by McsA. Nat. Chem. Bio. 2024, accepted. DOI: 10.1038/s41589-024-01720-3.
Y.-L- Zeng, L.-Y. Liu*, T.-Z. Ma, Y. Liu, B. Liu, W. Liu, Q.-H. Shen, C. Wu, Z.-W. Mao*. Iridium (III) Photosensitizers Induce Simultaneous Pyroptosis and Ferroptosis for Multi‐Network Synergistic Tumor Immunotherapy. Angew. Chem. Int. Ed. 2024, 63, e202410803. DOI: 10.1002/ange.202410803.
B Liu, B.-B. Liang, W.-D. Cao, X.-X. Su, Q. Cao*, Z.-W. Mao*. Platinum‐Metformin Conjugates Acting as Promising PD‐L1 Inhibitors through the AMP‐Activated Protein Kinase Mediated Lysosomal Degradation Pathway, Angew. Chem. Int. Ed.2024, 63, e202410586.DOI: 10.1002/ange.202410586.
W Liu, B.-C. Zhu, L.-Y. Liu, X.-Y. Xia, J. Jang, J. Dickerhoff, D. Yang*, Z.-W. Mao*. Solution structures and effects of a platinum compound successively bound MYC G-quadruplex. Nucleic Acids Res. 2024, 52, 9397. DOI: 10.1093/nar/gkae649.
T.-Z. Ma, L.-Y. Liu, Y.-L. Zeng, K. Ding, H. Zhang, W. Liu*, Q. Cao, W. Xia, X. Xiong*, C. Wu*, Z.-W. Mao*. G-quadruplex-guided cisplatin triggers multiple pathways in targeted chemotherapy and immunotherapy. Chem. Sci. 2024, 15, 9756. DOI: 10.1039/D4SC00643G.
M. Lv, C. Wu*, H.-K. Liu*, X Xue*, Z.-W. Mao*. Ruthenium(ii)–Arene Complex Triggers Immunogenic Ferroptosis for Reversing Drug Resistance. J. Med. Chem. 2024, accepted. DOI: 10.1021/acs.jmedchem.4c01467.
Y. Li*, B. Liu, Y. Zheng, M. Hu, L.-Y. Liu, C.-R. Li, W. Zhang*, Y.-X. Lai*, Z.-W. Mao*. Photoinduction of Ferroptosis and cGAS-STING Activation by a H2S-Responsive Iridium(III) Complex for Cancer-Specific Therapy. J. Med. Chem. 2024, 67, 18, 16235-16247
W.-J. Wang#, Y.-Y. Ling#, Y. Shi#, X.-W. Wu, X. Su, Z.-Q. Li*, Z.-W. Mao*, C.-P. Tan*. Identification of mitochondrial ATP synthase as the cellular target of Ru-polypyridyl-β-carboline complexes by affinity-based protein profiling. Natl. Sci. Rev. 2024, 11, nwae234
Q. Chen#, L.-Y. Liu#, Z. Tian#, Z. Fang#, K.-N. Wang, X. Shao, C. Zhang, W. Zou, F. Rowan, K. Qiu, B. Ji, J.-L. Guan, D. Li, Z.W. Mao*, J. Diao*. Mitochondrial nucleoid condensates drive peripheral fission through high membrane curvature. Cell Rep. 2023, 42(12), 113472. DOI: 10.1016/j.celrep.2023.113472.
Y. Ai, Z. Zhang, Y. Fei, R. Ye, A.S.Y. Law, Z.-W. Mao*, J. Liu*, Y. Li*, VW.W. Yam*. Rational design of platinum(II) complexes with orthogonally oriented triazolyl ligand with emission enhancement characteristics for cancer chemotherapy in vivo. Sci. China Chem. 2023, 66, 2878. DOI: 10.1007/s11426-023-1702-x.
M. Lv#, Y. Zheng#, J. Wu, Z. Shen, B. Guo, G. Hu, Y. Huang, J. Zhao, Y. Qian, Z. Su, C. Wu*, X. Xue*, H.-K. Liu*, Z.W. Mao*. Evoking Ferroptosis by Synergistic Enhancement of a Cyclopentadienyl Iridium-Betulin Immune Agonist. Angew. Chem. Int. Ed. 2023, 62(48), e202312897. DOI: 10.1002/anie.202312897.
B.-B. Liang#, Q. Liu#, B. Liu, H.-G. Yao, J. He, C.-F. Tang, K. Peng, X.-X. Su, Y. Zheng, J.-Y. Ding, J. Shen*, Q. Cao*, Z.W. Mao*. A Golgi-Targeted Platinum Complex Plays a Dual Role in Autophagy Regulation for Highly Efficient Cancer Therapy. Angew. Chem. Int. Ed. 2023, 62(44), e202312170. DOI: 10.1002/anie.202312170.
W. Lin#, Y. Liu#, J. Wang, Z. Zhao, K. Lu, H. Meng, R. Luoliu, X. He, J. Shen*, Z.W. Mao*, W. Xia*. Engineered Bacteria Labeled with Iridium(III) Photosensitizers for Enhanced Photodynamic Immunotherapy of Solid Tumors. Angew. Chem. Int. Ed. 2023, 62(43), e202310158. DOI: 10.1002/anie.202310158.
L.-Y. Liu#, T.-Z. Ma, Y.-L. Zeng, W. Liu, H. Zhang, Z.W. Mao*. Organic-Platinum Hybrids for Covalent Binding of G-Quadruplexes: Structural Basis and Application to Cancer Immunotherapy. Angew. Chem. Int. Ed. 2023, 62(36), e202305645. DOI: 10.1002/anie.202305645.
Z. Zhao#, X. Wang#, J. Wang#, Y. Li#, W. Lin, K. Lu, J. Chen, W. Xia*, Z.-W. Mao*. A nanobody–bioorthogonal catalyst conjugate triggers spatially confined prodrug activation for combinational chemo-immunotherapy. J. Med. Chem. 2023, 66, 11951-11964
Y. Zheng#, X.-X. Chen#, D.-Y. Zhang, W.-J. Wang, K. Peng, Z.-Y. Li, Z.W. Mao*, C.-P. Tan*. Activation of the cGAS-STING pathway by a mitochondrial DNA-targeted emissive rhodium(iii) metallointercalator. Chem. Sci. 2023, 14(25), 6890-6903. DOI: 10.1039/d3sc01737k.
W.-J. Wang#, C.-P. Tan*, Z.W. Mao*. Metals and inorganic molecules in regulating protein and nucleic acid phase separation. Curr. Opin. Chem. Biol. 2023, 74, 102308. DOI: 10.1016/j.cbpa.2023.102308.
K. Peng#, Y. Zheng#, W. Xia*, Z.W. Mao. Organometallic Anti-tumor Agents: Targeting from Biomolecules to Dynamic Bioprocesses. Chem. Soc. Rev. 2023, 52, 2790-2832. DOI: 10.1039/d2cs00757f.
X. Su, B. Liu, W. J. Wang, K. Peng, B.B. Liang, Y. Zheng, Q. Cao*, Z.W. Mao*. Disruption of Zinc Homeostasis by a Novel Platinum(IV)-Terthiophene Complex for Antitumor Immunity. Angew. Chem. Int. Ed. 2023, 62, e202216917. DOI: 10.1002/anie.202216917.
L.Y. Liu, T.Z. Ma, Y.L. Zeng, W. Liu*, Z.W. Mao*. Structural Basis of Pyridostatin and Its Derivatives Specifically Binding to G-Quadruplexes. J. Am. Chem. Soc., 2022, 144, 11878-11887. DOI: 10.1021/jacs.2c04775.
Z. Zhao, X. Tao, Y. Xie, Q. Lai, Y. Zheng, W. Lin, K. Lu, J. Wang, W. Xia*, Z.W. Mao*, In Situ Prodrug Activation by an Affibody-ruthenium Catalyst Hybrid for HER2-targeted Chemotherapy. Angew. Chem. Int. Ed. 2022, 61, e202202855. DOI: 10.1002/anie.202202855.
W.J. Wang, Y.Y. Ling, Y.M. Zhong, Z.Y. Li, C.P. Tan*, Z.W. Mao*. Ferroptosis-enhanced Cancer Immunity by a Ferrocene-appended Iridium(III) Diphosphine Complex. Angew. Chem. Int. Ed. 2022, e202115247. DOI: 10.1002/anie.202115247.
X. Su, W.J. Wang, Q. Cao*, H. Zhang, B. Liu, Y. Ling, X. Zhou, Z.W. Mao*. A Carbonic Anhydrase IX(CAIX)-Anchored Rhenium(I) Photosensitizer Evokes Pyroptosis for Enhanced Anti-tumor Immunity. Angew. Chem. Int. Ed. 2022, 61, e202115800. DOI: 10.1002/anie.202115800.
Y.Y. Ling, X.Y. Xia, L. Hao, W.J. Wang, H. Zhang, L.Y. Liu, W. Liu, Z.Y. Li, C.P. Tan*, Z.W. Mao*. Simultaneous Photoactivation of cGAS‐STING Pathway and Pyroptosis by Pt(II)-triphenylamine Complexes for Cancer Immunotherapy. Angew. Chem. Int. Ed. 2022, e202210988. DOI: 10.1002/anie.202210988.
K.N. Wang, L.Y. Liu, D. Mao, M.X. Hou, C.P. Tan, Z.W. Mao*, B. Liu*. A Nuclear-Targeted AIE Photosensitizer for Enzyme Inhibition and Photosensitization in Cancer Cell Ablation. Angew. Chem. Int. Ed. 2022, 61, e202114600. DOI: 10.1002/anie.202114600.
B.C. Zhu, J. He, X.Y. Xia, J. Jiang, W. Liu, L.Y. Liu, B.B. Liang, H.G. Yao, Z. Ke*, W. Xia*, Z.W. Mao*. Solution Structure of a Thrombin Binding Aptamer Complex with a Non-planar Platinum(II) Compound. Chem. Sci. 2022, 13, 8371-8379. DOI: 10.1039/D2SC01196D.
G.G. Yang, X.X. Su, B.B. Liang, Z.Y. Pan, Q. Cao*. Z.W. Mao*. Platinum-Ruthenium Hybrid Prodrug with Multi-enzymatic Activities for Chemo-catalytic Therapy of Hypoxic Tumors. Chem. Sci. 2022, 13, 11360-11367. DOI: 10.1039/D2SC03375E.
L. Hao, Y.Y. Ling, Z.X. Huang, Z.Y. Pan, C.P. Tan*, Z.W. Mao*. Real-time Tracking of ER Turnover during ERLAD by a Rhenium Complex via Lifetime Imaging. Natl. Sci. Rev. 2022, 9, nwab194. DOI: 10.1093/nsr/nwab194/6413567.
W.J. Wang, X. Mu, C.P. Tan*, Y.J. Wang, Y. Zhang*, G. Li*, Z.W. Mao*. Induction and Monitoring of DNA Phase Separation in Living Cells by a Light-Switching Ruthenium Complex. J. Am. Chem. Soc. 2021, 143, 11370-11381. DOI: 10.1021/jacs.1c01424.
B.C. Zhu, J. He, W. Liu*, X.Y. Xia, L.Y. Liu, B.B. Liang, H.G. Yao, B. Liu, L.N. Ji, Z.W. Mao*. Selectivity and Targeting of G-quadruplex Binders Activated by Adaptive Binding and Controlled by Chemical Kinetics. Angew. Chem. Int. Ed. 2021, 60, 15340-15343. DOI: 10.1002/anie.202104624.
L.Y. Liu, K.N. Wang, W. Liu*, Y.L. Zeng, M.X. Hou, J. Yang, Z.W. Mao*. Spatial Matching Selectivity and Solution Structure of Organic-Metal Hybrid to Quadruplex-Duplex Hybrid. Angew. Chem. Int. Ed. 2021, 60, 20833-20839. DOI: 10.1002/anie.202106256.
K. Peng, B.B. Liang, W. Liu, Z.W. Mao*. What Blocks More Anticancer Platinum Complexes From Experiment to Clinic: Major Problems and Potential Strategies from Drug Design Perspectives. Coord. Chem. Rev. 2021, 449, 214210. DOI: 10.1016/j.ccr.2021.214210.
X. Tao, L. Zhang, L. Du, R. Liao, H. Cai, K. Lu, Z. Zhao, Y. Xie, P.H. Wang, J.A. Pan, Y. Zhang, G. Li, J. Dai, Z.W. Mao*, W. Xia*. Allosteric Inhibition of SARS-CoV-2 3CL Protease by Colloidal Bismuth Subcitrate. Chem. Sci. 2021, 12, 14098-14102. DOI: 10.1039/D1SC03526F.
C.P. Tan*, Y.M. Zhong, L.N. Ji, Z.W. Mao*, Phosphorescent metal complexes as theranostic anticancer agents: combining imaging and therapy in a single molecule. Chem. Sci. 2021, 12, 2357-2367. DOI: 10.1039/d0sc06885c.
K.N. Wang, X. Shao, Z. Tian, L.Y. Liu, C. Zhang, C.P. Tan, J. Zhang, P. Ling, F. Liu, Q. Chen, J. Diao*, Z.W. Mao*. A Continuous Add-on Probe Reveals the Nonlinear Enlargement of Mitochondria in Light-Activated Oncosis. Adv. Sci. 2021, 8, 2004566. DOI: 10.1002/advs.202004566.
Y. Zheng, Y. Ling, D.Y. Zhang, C.P. Tan*, H. Zhang, G.G. Yang, H. Wang, L.N. Ji, Z.W. Mao*. Regulating Tumor N6-methyladenosine Methylation Landscape Using Hypoxia-Modulating OsSx Nanoparticles. Small, 2021, 17(1), 2005086. DOI: 10.1002/smll.202005086.
F.X. Wang, J.W. Liu, X.Q. Hong, C.P. Tan, L. Zhang*, W.H. Chen*, P. Sadler*, Z.W. Mao*. Anion-responsive Manganese Porphyrin Facilitates Chloride Transport and Induces Immunogenic Cell Death. CCS Chem. 2021, 3, 2527-2537. DOI:10.31635/ccschem. 021.202101212.
Q. Cao, D.J. Zhou, Z.Y. Pan, G.G. Yang, H. Zhang, L.N. Ji, Z.W. Mao*. CAIXplatins: Highly Potent Platinum(IV) Prodrugs Selective Against Carbonic Anhydrase IX for the Treatment of Hypoxic Tumors, Angew. Chem. Int. Ed. 2020, 59, 18556−18562. DOI: 10.1002/anie.202005362.
L.Y. Liu, H. Fang, Q. Chen, M.H. Chan, M. Ng, K.N. Wang, W. Liu, Z. Tian, J. Diao*, Z.W. Mao*, V.W. Yam*. Multiple-color Platinum Complex with Super-large Stokes Shift for Super-resolution Imaging of Autolysosome Escape, Angew. Chem. Int. Ed. 2020, 59, 19229−19236. DOI: 10.1002/anie.202007878.
L.Y. Liu, W. Liu, K.N. Wang, B.C. Zhu, X.Y. Xia, L.N. Ji, Z.W. Mao*, Quantitative Detection of G-Quadruplex DNA in Live Cells Based on Photon Counts and Complex Structure Discrimination. Angew. Chem. Int. Ed. 2020, 59, 9719−9726. DOI: 10.1002/anie.202002422.
Z.Y. Pan, C.P. Tan*, L.S. Rao, H. Z., Y. Zheng, L. Hao, L.N. Ji, Z.W. Mao*, Recoding the Cancer Epigenome by Intervening in Metabolism and Iron Homeostasis with Mitochondria-Targeted Rhenium(I) Complexes, Angew. Chem. Int. Ed., 2020,59, 2−10. DOI: 10.1002/anie.202008624.
J.H. Liang, Y. Zheng, X.W. Wu, C.P. Tan*, L.N. Ji, Z.W. Mao*. A Tailored Multifunctional Anticancer Nanodelivery System for Ruthenium-based Photosensitizers: Tumor Microenvironment Adaption and Remodeling. Adv. Sci. 2020, 7, 1901992. DOI: 10.1002/advs.201901992.

1. 一种金属离子亲和性环金属铱配合物及其制备方法和应用
中山大学
曹乾; 黄珂; 卢俊健; 毛宗万; 黄华珍
公开日期: 2025-05-09 申请日期: 2025-04-10 公开号: CN119954872A

2. 一种金属铱配合物及其制备方法和应用
中山大学
曹乾; 李政; 曹莞迪; 毛宗万
公开日期: 2025-04-18 申请日期: 2025-03-19 公开号: CN119841874A

3. 一种抗体偶联剂及其制备方法与应用
中山大学
夏炜; 招振楠; 陈俊; 毛宗万; 王馨语
公开日期: 2022-08-30 申请日期: 2022-03-10 公开号: CN114957346A

4. 一种环金属铱二甲双胍配合物及其制备方法和应用
中山大学
曹乾; 方浩吉; 杨靖; 毛宗万; 黄华珍
公开日期: 2020-08-25 申请日期: 2020-04-13 公开号: CN111574568A

5. 一种具有双光子吸收特性的铂配合物及其制备方法和应用
中山大学
毛宗万; 钟毅芳; 张航; 黄华珍; 曹乾
公开日期: 2017-12-01 申请日期: 2017-07-19 公开号: CN107417734A

6. 一种具有双光子吸收特性的铂配合物及其制备方法和应用
中山大学
毛宗万; 曹乾; 钟毅芳; 张航; 黄华珍
公开日期: 2017-12-01 申请日期: 2017-07-19 公开号: CN107417734A

7. 4,4’‑联吡啶桥联四核铂配合物在制备抗端粒酶阴性肿瘤药物中的应用
UNIV SUN YAT SEN
ZHAO YONG; ZHENG XIAOHUI; MAO ZONGWAN; XIA LIXIN
公开日期: 2017-10-20 申请日期: 2015-02-09 公开号: CN104693244B

8. 4，4'-联吡啶桥联四核铂配合物在制备抗端粒酶阴性肿瘤药物中的应用
SUN YAT-SEN UNIV
ZHAO YONG; ZHENG XIAOHUI; MAO ZONGWAN; XIA LIXIN
公开日期: 2016-08-18 申请日期: 2015-11-18 公开号: WO2016127681A1

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