专家介绍:
Chris graduated with B.Sc (2001) in Molecular Biology and a M.Sc (2005)in Computer Science from the National University of Singapore. He completed his PhD (2011) training at the University of Toronto with the world leading cell-cell communication and signal transduction expert, the late Prof. Tony Pawson, and made seminal contribution to our understanding of signaling network evolution related to organismal complexity and human diseases (Tan et al. Science 2009; Tan et al. Science Signaling 2009, Tan et al. Nature Method 2012). He subsequently moved to the Center of Molecular Medicine (CeMM) in Vienna, Austria and contributed to the development of a novel MS-based drug target deconvolution technology (Huber et al., Nature Method 2015) based on Cellular Thermal Shift Assay (CETSA). He was invited to join IMCB, A*STAR in 2015 by the inventor of CETSA, Prof. Pär Nordlund, and invented the first system-wide technology for studying the dynamic of protein complexes directly from intact cells and tissues (Tan et al. Science 2018). Chris had published more than 30 articles in international journals and conferences, including first or corresponding authors in Science, Nature Methods, Science Signaling and Bioinformatics journals. He has a H-index of 21 and his work had been highlighted in Science, Nature Genetics Review, Nature Methods, F1000Prime, Science Signaling, ACS Chemical Biology and Cell Systems. He had served as reviewer for Science, Nature Biotechnology, Nature Communication, and Bioinformatics.