精细化工

酶智能设计改造及其高效异源表达、发展新型酶催化理论与技术方法

1. Shen,Q.;Yan,J.;Han,Y.;Zhang,Z.*;Li,H.;Kong,D.;Shi,J.;Cui,C.*;Zhang,W.*,Peroxygenase Enabled Reductive Kinetic Resolution for the Enantioenrichment of Organoperoxides. Angew. Chem. Int. Ed.2024, e202401590.

2. Li,H.;Duan,P.*;Huang,Y.;Cui,C.;Hollmann,F.*;Ma,Y.;Wang,Y.;Zhang,J.;Liu,W.;Zhang*,W.,Vanadium-Containing Chloroperoxidase-Catalyzed Versatile Valorization of Phenols and Phenolic Acids. ACS Catalysis2024,14 (3),1733-1740.

3. Han,X.#;Chen,F.#;Li,H.;Ge,R.;Shen,Q.;Duan,P.*;Sheng,X.*;Zhang,W.*,Reaction engineering blocks ether cleavage for synthesizing chiral cyclic hemiacetals catalyzed by unspecific peroxygenase. Nature Communications2024,15 (1),1235.

4. Zhang,Y.;Zhou,X.;Cui,J.;Huang,Y.;Liu,X.;Zhang,Y.;Chen,B.;Zhang,W.*,Peroxygenase-catalysed selective and scalable synthesis of 25-hydroxy-grundmann's ketone and its derivatives. Molecular Catalysis2023,547,113389.

5. Li,Z.;Ge,R.;Tan,L.;Zhang,W.*;Zhang,Y.*,Photodecarboxylase Displayed on Microbial Cell-Surface for Enhanced Biocatalytic Performance. ChemCatChem2023, e202300494.

6. Li,H.;Zhang,Y.;Huang,Y.;Duan,P.;Ge,R.;Han,X.;Zhang,W.,A Simple Access to gamma- and epsilon-Keto Arenes via Enzymatic Divergent C horizontal line H Bond Oxyfunctionalization. Advanced Science2023,10 (34),e2304605.

7. Li,F.;Xia,A.*;Guo,X.;Huang,Y.;Zhu,X.;Zhang,W.*;Chen,R.;Liao,Q.,Photo-driven enzymatic decarboxylation of fatty acids for bio-aviation fuels production in a continuous microfluidic reactor. Renewable and Sustainable Energy Reviews2023,183,113507.

8. Huang,Y.;Li,H.;Zhang,P.;Zhang,Y.;Duan,P.;Zhang,W.*,H2O2-driven enzymatic oxyfunctionalization of tertiary C–H bonds. Chemical Communications2023,59 (60),9219-9222.

9. Gomez de Santos,P.;González-Benjumea,A.;Fernandez-Garcia,A.;Aranda,C.;Wu,Y.;But,A.;Molina-Espeja,P.;Maté,D. M.;Gonzalez-Perez,D.;Zhang,W.;Kiebist,J.;Scheibner,K.;Hofrichter,M.;Świderek,K.;Moliner,V.;Sanz-Aparicio,J.;Hollmann,F.;Gutiérrez,A.;Alcalde,M.,Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids. Angew. Chem. Int. Ed.2023,62 (9),e202217372.

10 Li,H.;Younes,S. H. H.;Chen,S.;Duan,P.*;Cui,C.;Wever,R.;Zhang,W.*;Hollmann,F.*,Chemoenzymatic Hunsdiecker-Type Decarboxylative Bromination of Cinnamic Acids. ACS Catalysis 2022,12 (8),4554-4559.