生物医药

生物过程检测与控制；生物过程优化与放大；微生物代谢调控

[1] Xiwei Tian, Xuehua Liu, Yifan Zhang, Yang Chen, Haifeng Hang*, Ju Chu, Yingping Zhuang. Metabolic engineering coupled with adaptive evolution strategies for the efficient production of high-quality L-lactic acid by Lactobacillus paracasei. Bioresource Technology. 2021, 323: 124549.
[2] Yang Chen1, Xiwei Tian1, Qianhui Li, Ya Li, Ju Chu, Haifeng Hang*, Yingping Zhuang. Target-site directed rational high-throughput screening system for high sophorolipids production by Candida bombicola. Bioresource Technology. 2020, 315: 123856.
[3] Ali Mohsin, Jingyun Sun, Imran Mahmood Khan, Haifeng Hang*, Muhammad Tariq, Xiwei Tian, Waqas Ahmed, Sobia Niazi, Yingping Zhuang, Ju Chu, Muhammad Zubair Mohsin, Salim-ur-Rehman, Meijin Guo*. Sustainable biosynthesis of curdlan from orange waste by using Alcaligenes faecalis: A systematically modeled approach. Carbohydrate Polymers. 2019, 205: 626-635.
[4] Xiwei Tian, Yuting Shen, Yingping Zhuang, Wei Zhao, Haifeng Hang*, Ju Chu*． Kinetic analysis of sodium gluconate production by Aspergillus niger with different inlet oxygen concentrations．Bioprocess and Biosystems Engineering. 2018, 41(11): 1697-1706.
[5] Yuting Shen, Xiwei Tian, Wei Zhao, Haifeng Hang*, Ju Chu*. Oxygen-enriched fermentation of sodium gluconate by Aspergillus niger and its impact on intracellular metabolic flux distributions. Bioprocess and Biosystems Engineering. 2018, 41(1): 77-86.
[6] Xiwei Tian, Gang Zhou, Weifei Wang, Ming Zhang, Haifeng Hang*, Ali Mohsin, Ju Chu, Yingping Zhuang, Siliang Zhang. Application of 8-parallel micro-bioreactor system with non-invasive optical pH and DO biosensor in high-throughput screening of l-lactic acid producing strain. Bioresources and Bioprocessing. 2018, 5:20.
[7] Qin Zhang, Jingyun Sun, Zejian Wang*, Haifeng Hang*, Wei Zhao, Yingping Zhuang, Ju Chu. Kinetic analysis of curdlan production by Alcaligenesfaecalis with maltose, sucrose, glucose and fructose as carbon sources. Bioresource Technology. 2018, 259: 319-324.

[1] 一种在线监测及优化黑曲霉发酵生产葡萄糖酸钠的方法, ZL201710039712.8
[2] 一种组合式消泡桨及使用组合式消泡桨的微型生物反应器, ZL201610643053.4
[3] 基于氧化还原电位自动反馈调控厌氧发酵生产乙醇的方法, ZL200810200505.7

[1] 高通量优选仪器开发及应用，国家重大科学仪器设备开发专项，课题负责人， 662.67万
[2] 高版本底盘细胞分析与评价，国家重点研发计划，子课题负责人，41.0万
[3] 红外检测仪研制及应用研究，国家科技支撑计划，子课题负责人， 38.4万

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