精细化工,生物医药

生物催化与发酵工程

1、Wen P, Wu D, Zheng P*, Chen P-C, Liu S, Fu Y. Highly Efficient Biosynthesis of Heliotropin by Engineered Escherichia coli Coexpressing Trans-Anethole Oxygenase and Formate Dehydrogenase [J]. Journal of agricultural and food chemistry[J]. 2019; 67:14121-14128
2、Wang C-C, Zheng P*, Chen P-C. Construction of synthetic pathways for raspberry ketone production in engineered Escherichia coli. Applied Microbiology and Biotechnology [J]. 2019; 103:3715:3725
3、Ren D-X, Chen P-C, Zheng P*, Xu Z-N. pH/redox dual response nanoparticles with poly-gamma-glutamic acid for enhanced intracellular drug delivery. Colloids and Surfaces A-physicochemical and engineering aspects [J]. 2019; 577:412-420
4、Wang D-Q, Zheng P*, Chen P-C. Production of a Recombinant α-L-Rhamnosidase from Aspergillus niger CCTCC M 2018240 in Pichia pastoris. Applied Biochemistry and Biotechnology [J]. 2019; 189:1020–1037
5、Chen P-C, Z H, Zheng P*. Direct Biodegradation of Eugenol into Coniferyl Aldehyde and Other higher value-added Products by Gibberella fujikuroi ZH-34. Electronic Journal of Biotechnology [J]. 2019; 38:32-39
6、Zhao M-Tao, Zheng P*, Chen P-C, Liu S-Q. Biosynthesis of heliotropin by a novel strain of serratia liquefaciens. Applied Biochemistry and Biotechnology[J]. 2017; 183:1282–1294
7、Chen P-C, Tao S-T, Zheng P*. Efficient and repeated production of succinic acid by turning sugarcane bagasse into sugar and support. Bioresource Technology [J]. 2016; 211: 406–413
8、Liu W, Zheng* P, Yu F, Yang Q. A two-stage process for succinate production using genetically engineered Corynebacterium acetoacidophilum. Process Chemistry [J]. 2015, 50:1692-1700
9、Yan Q, Zheng P*, Dong J-J, Sun Z-H. Aibrous bed bioreactor to improve the productivity of succinic acid by Actinobacillus succinogenes. Journal of Chemical Technology and Biotechnology [J]. 2014, 89:1760-1766
10、Zheng P*, Zheng K-k, Yan Q, Xu Y*, Zhi Hao Sun, Enhanced succinic acid production by Actinobacillus succinogenes after genome shuffling. Journal of Industrial Microbiology and Biotechnology [J]. 2013, 40:831-840

1、郑璞; 陈鹏程; 董文华. 一种Lasiodiplodia iranensis菌及其发酵产茉莉酸的方法.授权号: ZL 201710616357.6, 2019-07-02
2、郑璞; 陈鹏程; 张慧. 一种藤仓赤霉菌及其转化丁香酚合成松柏醛的方法. 授权号: ZL 201610296678.8, 2019-06-07
3、郑璞; 王杰.一株以葡萄糖为底物合成粘康酸的大肠杆菌工程菌. 授权号: ZL 2014103106436, 2018-09-26
4、郑璞; 陈鹏程; 查鑫华.一种将右旋糖酐发酵废液用于丁二酸发酵生产的方法. 授权号: ZL 201510685173.6，2018-09-18
5、郑璞; 淘声涛; 查鑫华. 一种以甘蔗渣原料发酵生产丁二酸的方法. 授权号: ZL 201510387997.5, 2018-01-23
6、郑璞; 姚红涛. 一种甲基营养菌及其发酵生产吡咯喹啉醌的方法. 授权号: ZL 201410087026.4, 2016-01-20
7、Pu Zheng, Hui Li, Xinglin Wang, et al. An Amycolatopsis sp. Strain and Methods of Using the Same for Vanillin Production. US 9115377B2, 2015-08-25
8、郑璞; 颜强. 以棉纤维材料固定琥珀酸放线杆菌发酵生产丁二酸的方法. 授权号: ZL 201310401535.5, 2014-11-26
9、郑璞; 于芳; 杨倩. 一株嗜乙酰乙酸棒杆菌及其产丁二酸的方法. 授权号: ZL 201210094742.6，2013-04-17
10、郑璞; 张坤坤. 一株产琥珀酸的琥珀酸放线杆菌.授权号:ZL 01210056568.6, 2013-05-15

1、江苏省产学研项目 发酵法高效生产丁二酸的关键技术研究；江苏省自然科学基金项目 微生物合成丁二酸高产菌株选育与代谢调控研究
2、企业合作项目：微生物发酵法生产茉莉酮酸、微生物发酵生产吡咯喹啉醌、微生物一步转化法制备香兰素
3、企业合作项目：生物法合成洋茉莉醛
4、企业合作项目：白酒糟发酵生产丁二酸技术开发、葡萄糖为原料生产丁二酸
5、完成国家十二五、十五科技项目：非粮原料（玉米秸秆）综合利用产聚谷氨酸研究、生物转化法生产香草醛
6、参与完成国家863项目：利用可再生资源厌氧发酵固定二氧化碳制备丁二酸、谷氨酸发酵高产菌种选育和过程优化控制技术——基因组改组技术选育谷氨酸生产菌种
7、参与完成973计划：非水相不对称生物催化、国家自然科学基金：生物催化不对称还原合成手性药物的关键科学技术问题

技术咨询