论文著作：
1. Li, Y.; Wang, H.; Zhang, L.; Ding, Z.; Xu, S.; Gu, Z.; Shi, G. Efficient Genome Editing in Bacillus licheniformis Mediated by a Conditional CRISPR/Cas9 System. Microorganisms 2020, 8.5, 754.
2. Li, Y.; Liu, X.; Zhang, L.; Ding, Z.; Xu, S.; Gu, Z.; Shi, G. Transcriptional changes in the xylose operon in bacillus licheniformis and their use in fermentation optimization. International Journal of Molecular Sciences 2019, 20, doi:10.3390/ijms20184615.
3. Li, Y.; Wang, H.; Lu, J.; Chu, A.; Zhang, L.; Ding, Z.; Xu, S.; Gu, Z.; Shi, G. Preparation of immobilized lipase by modified polyacrylonitrile hollow membrane using nitrile-click chemistry. Bioresource Technology 2019, 274, 9-17, doi:10.1016/j.biortech.2018.11.075.
4. Li, Y.; Jin, K.; Zhang, L.; Ding, Z.; Gu, Z.; Shi, G. Development of an inducible secretory expression system in Bacillus licheniformis based on an engineered xylose operon. Journal of Agricultural and Food Chemistry 2018, 66, 9456-9464, doi:10.1021/acs.jafc.8b02857.
5. Li, Y.; Gu, Z.; Zhang, L.; Ding, Z.; Shi, G. Inducible expression of trehalose synthase in Bacillus licheniformis. Protein Expression and Purification 2017, 130, 115-122, doi:10.1016/j.pep.2016.10.005.
6. Li, Y.; Xu, J.; Zhang, L.; Ding, Z.; Gu, Z.; Shi, G. Investigation of debranching pattern of a thermostable isoamylase and its application for the production of resistant starch. Carbohydrate Research 2017, 446, 93-100, doi:10.1016/j.carres.2017.05.016.
7. Li, Y.; Zhang, L.; Ding, Z.; Gu, Z.; Shi, G. Engineering of isoamylase: improvement of protein stability and catalytic efficiency through semi-rational design. Journal of Industrial Microbiology & Biotechnology 2016, 43, 3-12, doi:10.1007/s10295-015-1708-4.
8. Li, Y.; Zhang, L.; Ding, Z.; Shi, G. Constitutive expression of a novel isoamylase from Bacillus lentus in Pichia pastoris for starch processing. Process Biochemistry 2013, 48, 1303-1310, doi:10.1016/j.procbio.2013.07.001.
9. Li, Y.; Niu, D.; Zhang, L.; Wang, Z.; Shi, G. Purification, characterization and cloning of a thermotolerant isoamylase produced from Bacillus sp CICIM 304. Journal of Industrial Microbiology & Biotechnology 2013, 40, 437-446, doi:10.1007/s10295-013-1249-7.
10. Li, Y.; Zhang, L.; Niu, D.; Wang, Z.; Shi, G. Cloning, expression, characterization, and biocatalytic investigation of a novel bacilli thermostable type i pullulanase from Bacillus sp CICIM 263. Journal of Agricultural and Food Chemistry 2012, 60, 11164-11172, doi:10.1021/jf303109u.
11. Zhang, Y.; Li, Y.; Xiao, F.; Wang, H.; Zhang, L.; Ding, Z.; Xu, S.; Gu, Z.; Shi, G., Engineering of a biosensor in response to malate in Bacillus licheniformis. ACS synthetic biology 2021, in press.
12. Xu, Y.; Li, Y.; Li, L.; Zhang, L.; Ding, Z.; Shi, G., Reductase-catalyzed tetrahydrobiopterin regeneration alleviates the anti-competitive inhibition of tyrosine hydroxylation by 7,8-dihydrobiopterin. Catalysis Science & Technology 2021, 11, 3128-3140.
13. Xiao, F.; Li, Y.; Zhang, Y.; Wang, H.; Zhang, L.; Ding, Z.; Gu, Z.; Xu, S.; Shi, G., A new CcpA binding site plays a bidirectional role in carbon catabolism in Bacillus licheniformis. Iscience 2021, 24.
14. Wu, Z.; Li, Y.; Zhang, L.; Ding, Z.; Shi, G., Microbial production of small peptide: pathway engineering and synthetic biology. Microbial Biotechnology 2021.
15. Lu, J.; Li, Y.; Zhu, H.; Shi, G., SiO2-coated Fe3O4 Nanoparticle/Polyacrylonitrile beads for one-step lipase immobilization. ACS Applied Nano Materials 2021.
李由然
江苏省
研究领域：
生物医药
研究方向：
地衣芽孢杆菌的合成生物学
所在单位：
江南大学
