论文著作：
1. Zou LL, Li JR, Li H, Tan JL, Wang MX, Liu NN, Gao RM, Yan HY, Wang XK, Dong B, Li YH, Peng ZG*. TGF-β isoforms inhibit hepatitis C virus propagation in transforming growth factor beta/SMAD protein signalling pathway dependent and independent manners. J Cell Mol Med. 2021 Apr;25(7):3498-3510.
2. Lv XQ, Zou LL, Tan JL, Li H, Li JR, Liu NN, Dong B, Song DQ, Peng ZG*. Aloperine inhibits hepatitis C virus entry into cells by disturbing internalisation from endocytosis to the membrane fusion process. Eur J Pharmacol. 2020 Sep 15, 883：173323.
3. Jiang X#, Tan J#, Wang Y, Chen J, Li J, Jiang Z, Quan Y, Jin J, Li Y, Cen S, Li Y*, Peng Z*, Li Z*. 2-((4-Arylpiperazin-1-yl)methyl)benzonitrile Derivatives as Orally Available Inhibitors of Hepatitis C Virus with a Novel Mechanism of Action. J Med Chem. 2020 Jun 11;63(11):5972-5989.
4. Li H#, Tan JL#, Li JR#, Liu NN, Chen JH, Lv XQ, Zou LL, Dong B, Peng ZG*, Jiang JD*. A proof-of-concept study in HCV-infected Huh7.5 cells for shortening the duration of DAA-based triple treatment regimens. Biomed Pharmacother. 2019 Aug; 116: 108976.
5. Wu ZY#, Li H #, Li JR, Lv XQ, Jiang JD, Peng ZG*. Farnesoid X receptor agonist GW4064 indirectly inhibits HCV entry into cells via down-regulating scavenger receptor class B type I. Eur J Pharmacol, 2019, 15 June, 853: 111-120.
6. Huang MH#, Li H#, Xue R, Li JR, Wang LH, ChengJJ, Wu ZY, Li WJ, Chen JH, Lv XQ, Li Q, Lan P, Zhao LM, Yang YF*, Peng ZG*, Jiang JD*. Up-regulation of glycolipid transfer protein by bicyclol causes spontaneous restriction of hepatitis C virus replication. Acta Pharmaceutica Sinica B. 2019 Jul; 9(4):769-781.
7. Li H, Li JR, Huang MH, Chen JH, Lv XQ, Zou LL, Tan JL, Dong B, Peng ZG*, Jiang JD* . Bicyclol attenuates liver inflammation induced by infection of hepatitis C virus via repressing ROS-mediated activation of MAPKs/NF-κB signaling pathway. Front. Pharmacol. 2018, Dec 19; 9:1438
8.Zhang X#, Lv XQ#, Tang S, Mei L, Li YH, Zhang JP, Jiang JD, Peng ZG*, Song DQ*. Discovery and evolution of aloperine derivatives as a new family of HCV inhibitors with novel mechanism. Eur J Med Chem. 2018 Jan 1;143:1053-1065.
9. Ji XY#, Chen JH#, Zheng GH, Huang MH, Zhang L, Jin J, Yi H, Jiang JD, Peng ZG*, Li ZR*. Design and Synthesis of Cajanine Analogues against Hepatitis C Virus through Down-regulating Host Chondroitin Sulfate N-acetylgalactosaminyltransferase 1. J Med Chem. 2016 Nov 23;59(22):10268-10284
10. Cheng JJ, Li JR, Huang MH, Ma LL, Wu ZY, Jiang CC, Li WJ, Li YH, Han YX, Li H, Chen JH, Wang YX, Song DQ, Peng ZG*, Jiang JD*. CD36 is a co-receptor for hepatitis C virus E1 protein attachment. Sci Rep. 2016 Feb 22;6:21808.
彭宗根
北京市
研究领域：
生物医药
研究方向：
抗肝炎、抗病毒药物药理学
所在单位：
中国医学科学院北京协和医学院
