生物医药

丝状真菌天然药物分子生物合成与代谢工程

1. Ren P, Rajkumar SS, Zhang T, Sui H, Masters PS, Martinkova N, Kubátová A, Pikula J, Chaturvedi S, Chaturvedi V. A common partitivirus infection in United States and Czech Republic isolates of bat white-nose syndrome fungal pathogen Pseudogymnoascus destructans.Sci Rep. 2020,10(1):13893.
2. Zhang T, Ren P, De Jesus M, Chaturvedi V, Chaturvedi S. Green Fluorescent Protein Expression in Pseudogymnoascus destructans to Study Its Abiotic and Biotic Lifestyles. Mycopathologia,2018,183(5):805-814.
3. Gao SS#, Zhang T#, Garcia-Borràs M, Hung YS, Billingsley JM, Houk KN, Hu Y, Tang Y. Biosynthesis of heptacyclic duclauxins requires extensive redox modifications of the phenalenone aromatic polyketide.J Am Chem Soc, 2018,140(22):6991-6997.（#co-fisrt author）
4. Zhang T#, Wan J#, Zhan Z, Bai J, Liu B, Hu Y. Activation of an unconventional meroterpenoid gene cluster in Neosartorya glabra leads to the production of new berkeleyacetals.Acta Pharmaceutica Sinica B,2018,8(3):478-487.（#co-fisrt author）
5.Zhang F, Liu H,Zhang T, Pijning T, Yu L, Zhang W, Liu W, Meng X.Biochemical and genetic characterization of fungal proline hydroxylase in echinocandin biosynthesis. Appl Microbiol Biotechnol. 2018,102(18):7877-7890.
6.Bai J#, Yan D#, Zhang T, Guo Y, Liu Y, Zou Y, Tang M, Liu B, Wu Q, Yu S, Tang Y, Hu Y. A Cascade of Redox Reactions Generates Complexity in the Biosynthesis of the Protein Phosphatase-2 Inhibitor Rubratoxin A. Angew Chem Int Ed Engl. 2017,56(17):4782-4786.
7. Zhang T, Ren P, Chaturvedi V, Chaturvedi S. Novel Trichoderma polysporum strain for the biocontrol of Pseudogymnoascus destructans, the fungal etiologic agent of bat White Nose Syndrome.PLoS One, 2015,10(10):e0141316.
8. Zhang T, Ren P, Chaturvedi V, Chaturvedi S. Development of an Agrobacterium-mediated transformation system for the cold-adapted fungi Pseudogymnoascus destructans and P. pannorum.Fungal Genet Biol,2015,81:73-81.
9. Zhang T#, Victor TR#, Rajkumar SS, Li X, Okoniewski JC, Hicks AC, Davis AD, Broussard K, LaDeau SL, Chaturvedi S, Chaturvedi V. Mycobiome of the bat white nose syndrome affected caves and mines reveals diversity of fungi and local adaptation by the fungal pathogen Pseudogymnoascus (Geomyces) destructans. PLoS One. 2014,9(9):e108714.（#co-fisrt author）
10. Zhuo Y#, Zhang T#, Wang Q, Cruz-Morales P, Zhang B, Liu M, Barona-Gómez F, Zhang L. Synthetic biology of avermectin for production improvement and structure diversification. Biotechnol J. 2014,9(3):316-25.（#co-fisrt author）
11. Zhang T#, Zhuo Y#, Jia X, Liu J, Gao H, Song F, Liu M, Zhang L. Cloning and characterization of the gene cluster required for beauvericin biosynthesis in Fusarium proliferatum. Sci China Life Sci. 2013,56(7):628-37.（#co-fisrt author）
12. Zhang T, Jia X, Zhuo Y, Liu M, Gao H, Liu J, Zhang L. Cloning and characterization of a novel 2-ketoisovalerate reductase from the beauvericin producer Fusarium proliferatum LF061. BMC Biotechnol. 2012,12:55.