张骁 研究员 博士 广东省 研究领域: 生物医药 研究方向: hiPSCs application development for HCS / HTS drug screening and clinical application Cell Signalling in Innate Immunity and Inflammation for cardiovascular application 所在单位: 中国科学院广州生物医药与健康研究院

基本信息

所在单位:
中国科学院广州生物医药与健康研究院
单位类型:
科研机构
职务:
研究员
职称:
研究员
最高学历:
博士
教育经历:
2005-2008 Doctora·Research Student, PhD, Medica·School, Sheffield
2002-2005 Bachelor´s Degree, Bsci, Biochemistry, University of Sheffield
工作经历:
2013 GIBH
2010-2013 Product Development/Portfolio Manager, R&D, Biotherapeutics, Molecular Devices
2009-2010 Senior Scientist, R&D, Drug Discovery, Leica
2008-2009 Non-Clinica·Research Fellow , Roya·Hallamshire Hospital
专家荣誉:
2012 - Co-Investigator/Applicant , BBSRC, (grant No. BB/J009687) industry application grant: Defining TILRR regulation of distinct IL-1RI responses using systems biology – £1,2M
2010 - R&D Exceptional Science Award,

科研能力

研究领域:
生物医药
研究方向:
hiPSCs application development for HCS / HTS drug screening and clinical application
Cell Signalling in Innate Immunity and Inflammation for cardiovascular application
论文著作:
ZHANG X, MONTAGUT PINO G, SHEPHARD F, KISS-TOTH E and QWARNSTROM EE, 2012. Distinct control of MyD88-dependent and AKT-regulated responses by the IL-1R1 co-receptor, TILRR. Journal of Biological Chemistry. 287(15), 12348-52 Cover of Journal issue April 6th, 2012
ZHANG, XIAO, SHEPHARD, FREYA, KIM, HONG B, PALMER, IAN R, MCHARG, SELINA, FOWLER, GREGORY J S, O'NEILL, LUKE A J, KISS-TOTH, ENDRE and QWARNSTROM, EVA E, 2010. TILRR, a novel IL-1RI co-receptor, potentiates MyD88 recruitment to control Ras-dependent amplification of NF-kappaB. The Journal of biological chemistry. 285(10), 7222-32
Monica Neilan, Xiao Zhang, Sheila Francis, Eva E Qwarnstrom, 2010. BAS/BSCR51 Control of vascular cell inflammatory responses through TILRR, an interleukin 1 co-receptor. Heart. 10; 96(17):e27.
M Neilan, X Zhang, T Steiner, J Boyle, S Francis, D Haskard, E Qwarnstrom, 2012. TILRR Functional Mutants Selectively Inhibit Inflammatory and Anti-Apoptotic Responses. Heart. 12; 98(10):e6
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