论文著作：
[1] Fang LX, Hao XY, Fan J, Liu XL, Chen YR, Wang L, Huang XY, Song H, Cao YX*. Genome-scale CRISPRi screen identifies pcnB repression conferring improved physiology for overproduction of free fatty acids in Escherichia coli. Nat. Commun., 2025, 16:3060.
[2] Fang LX, Fan J, Luo SL, Chen YR, Wang CY, Cao YX*, Song H*. Genome-scale target identification in Escherichia coli for high-titer production of free fatty acids. Nat Commun. 2021, 12(1):4976.
[3] Chen YR, Duan QY, Wang L, He QX, Fang LX, Xiao L, Song H, Cao YX*. Genome-scale CRISPRi and base-editing libraries for genetic decoding and strain engineering in Shewanella. Trends Biotechnol., 2025. DOI: 10.1016/j.tibtech.2025.10.005.
[4] Fang LX#, Liu XL#, Chen ZX, Zhang JQ, Wang L, Cao YX*. Genome-scale overexpression screen reveals membrane homeostasis as a key determinant for free fatty acids overproduction in Escherichia coli. Metab. Eng., 2025, 92:13-21.
[5] Fang LX#, Chen YR#, He QX#, Wang LX, Duan QY, Huang CC, Song H, Cao YX*. Mining novel gene targets for improving tolerance to furfural and acetic acid in Yarrowia lipolytica using whole-genome CRISPRi library. Bioresource Technol. 2024, 403:130764.
[6] Bai QY#, Cheng S#, Zhang JL, Li MX, Cao YX*, Yuan YJ. Establishment of genomic library technology mediated by nonhomologous end joining mechanism. SCI CHINA LIFE SCI. 2021, 64(12):2114-2128.
[7] Fang LX#, Wen PS#, Zhang JQ, Cao YX*. Dynamic regulation of efflux pump protein AcrA by quorum sensing system to improve free fatty acids production in Escherichia coli. Biotechnol. Bioeng., 2025, 122(9):2499-2510.
[8] Huang CC#, Chen YR#, Cheng S, Li MX, Wang LX, Cheng MJ, Li F, Cao YX*, Song H*. Enhanced acetate utilization for value-added chemicals production in Yarrowia lipolytica by integration of metabolic engineering and microbial electrosynthesis. Biotechnol Bioeng, 2023, 120(10):3013-3024.
[9] Li Y#, Li YY#, Chen YR, Cheng MJ, Yu H, Song H*, Cao YX*. Coupling riboflavin de novo biosynthesis and cytochrome expression for improving extracellular electron transfer efficiency in Shewanella oneidensis. Biotechnol Bioeng, 2022, 119(10):2806-2818.
[10] Zhang JL#, Bai QY#, Peng YZ, Fan J, Jin CC, Cao YX*, Yuan YJ. High production of triterpenoids in Yarrowia lipolytica through manipulation of lipid components. Biotechnol Biofuels. 2020, 13: 133.
曹英秀
天津市
研究领域：
生物医药
研究方向：
生物制药、合成生物学
所在单位：
天津大学
