生物医药

细菌合成生物学，肠道益生菌

序列元件;tail pcr;种子特异性启动子

Lactococcus Lactis;Metabolic Engineering;Acid Tolerance;Nisin;Nisin Production;Acid Resistance;Soybean;Liverwort;Transcriptome Analysis;Synthetic Biology

2020年以来发表了十余篇高水平研究论文

参编教材有《生物化学》；《生命科学与生物技术》；

1 Wu S, Bu X, Chen D, Wu X, Wu H, Caiyin Q, Qiao J. Molecules-mediated bidirectional interactions between microbes and human cells. NPJ Biofilms Microbiomes. 2025 Mar 4;11(1):38. doi: 10.1038/s41522-025-00657-2. PMID: 40038292; PMCID: PMC11880406.
2 Lu J, Wu H, Wu S, Wang S, Fan H, Ruan H, Qiao J, Caiyin Q, Wen M. Salmonella: Infection mechanism and control strategies. Microbiol Res. 2025 Mar;292:128013. doi: 10.1016/j.micres.2024.128013. Epub 2024 Dec 12. PMID: 39675139.
3 Chen C, Zhang Y, Chen R, Liu K, Wu H, Qiao J, Caiyin Q. Development of a Pre-Modification Strategy to Overcome Restriction-Modification Barriers and Enhance Genetic Engineering in Lactococcus lactis for Nisin Biosynthesis. Int J Mol Sci. 2025 Feb 28;26(5):2200. doi: 10.3390/ijms26052200. PMID: 40076820; PMCID: PMC11900431.
4 Hu L, Lu J, Fan H, Niu C, Han Y, Caiyin Q, Wu H, Qiao J. FAS mediates apoptosis, inflammation, and treatment of pathogen infection. Front Cell Infect Microbiol. 2025 Apr 22;15:1561102. doi: 10.3389/fcimb.2025.1561102. PMID: 40330016; PMCID: PMC12052831.
5 Chen C, Zhang Y, Wu H, Qiao J, Caiyin Q. Advances in Diversity, Evolutionary Dynamics and Biotechnological Potential of Restriction-Modification Systems. Microorganisms. 2025 May 14;13(5):1126. doi: 10.3390/microorganisms13051126. PMID: 40431298; PMCID: PMC12114051.
6 Wang S, Zhou J, Zhan C, Qiao J, Caiyin Q, Huang M. Fine-Tuning the Function of Farnesene Synthases for Selective Synthesis of Farnesene Stereoisomers. J Agric Food Chem. 2024 Dec 11;72(49):27355-27364. doi: 10.1021/acs.jafc.4c09515. Epub 2024 Nov 26. PMID: 39588907; PMCID: PMC11638952.
7 Wu S, Qu Z, Chen D, Wu H, Caiyin Q, Qiao J. Deciphering and designing microbial communities by genome-scale metabolic modelling. Comput Struct Biotechnol J. 2024 Apr 22;23:1990-2000. doi: 10.1016/j.csbj.2024.04.055. PMID: 38765607; PMCID: PMC11098673.
8 E Y, Li W, Guo H, Zhang X, Caiyin Q, Yuan Y. Dynamic profiling of metabolite changes and health-promoting functions in 'yuling paste' during nine steaming and nine sun-drying processes. Food Chem X. 2024 Jul 18;23:101668. doi: 10.1016/j.fochx.2024.101668. PMID: 39139487; PMCID: PMC11321412.
9 Yan X, David SD, Du G, Li W, Liang D, Nie S, Ge M, Wang C, Qiao J, Li Y, Caiyin Q. Biological Properties of Sandalwood Oil and Microbial Synthesis of Its Major Sesquiterpenoids. Biomolecules. 2024 Aug 8;14(8):971. doi: 10.3390/biom14080971. PMID: 39199359; PMCID: PMC11352278.
10 Wang S, Zhan C, Nie S, Tian D, Lu J, Wen M, Qiao J, Zhu H, Caiyin Q. Enzyme and Metabolic Engineering Strategies for Biosynthesis of α-Farnesene in Saccharomyces cerevisiae. J Agric Food Chem. 2023 Aug 23;71(33):12452-12461. doi: 10.1021/acs.jafc.3c03677. Epub 2023 Aug 13. PMID: 37574876.

1. 石墨烯改性APP/PERM/EL水性聚氨酯阻燃涂料及制备方法
UNIV TIANJIN
QIAO JIANJUN; ZHAO XINGWANG; LI WEI; XU RANRAN; CAIYINQINGGELE; ZHAO XIULI; WU HAO
公开日期: 2019-06-07 申请日期: 2017-05-05 公开号: CN107151522B

2. 一种山梨酸钾改性水性聚氨酯抗菌复合面料及制备方法
UNIV TIANJIN
CAIYINQINGGELE; XU RANRAN; LI WEI; QIAO JIANJUN; LIU JIAHENG; ZHAO XINGWANG; WU HAO
公开日期: 2019-05-10 申请日期: 2017-06-03 公开号: CN107100009B

3. 一种具有优良抗氧化活性的香菇寡糖及制备方法
天津大学
乔建军; 宋倩倩; 薛艳婷; 田丽; 朱宏吉; 杨慧; 张雷; 财音青格乐
公开日期: 2018-07-10 申请日期: 2017-12-26 公开号: CN108265092A

4. 种山梨酸钾改性水性聚氨酯抗菌复合面料及制备方法
UNIV TIANJIN
QIAO JIANJUN; ZHAO XINGWANG; XU RANRAN; CAIYINQINGGELE; LIU JIAHENG; WU HAO; LI WEI
公开日期: 2017-08-29 申请日期: 2017-06-03 公开号: CN107100009A

5. 乳酸乳球菌乳亚种YF11的非编码小RNA s013
天津大学
赵秀丽; 财音青格乐; 周丹丹; 李艳妮; 乔建军; 吴昊; 朱宏吉
公开日期: 2017-08-15 申请日期: 2016-11-29 公开号: CN107043772B

6. 乳酸乳球菌乳亚种YF11的非编码小RNAs087
天津大学
李艳妮; 赵秀丽; 周丹丹; 刘家亨; 财音青格乐; 朱宏吉
公开日期: 2017-08-15 申请日期: 2016-11-29 公开号: CN107043771A

7. 种有助于肠道蠕动的按摩装置
UNIV TIANJIN
TIAN LI; CAIYINQINGGELE; QIAO JIANJUN; LI WEIGUO; ZHAO XIULI; XIAO MI; ZHU HONGJI
公开日期: 2017-06-20 申请日期: 2017-01-05 公开号: CN106859935A

8. 乳酸乳球菌乳亚种YF11的非编码小RNAs042
UNIV TIANJIN
QIAO JIANJUN; ZHOU DANDAN; ZHAO XIULI; CAIYINQINGGELE; LI YANNI; ZHU HONGJI; LIU JIAHENG
公开日期: 2017-05-17 申请日期: 2016-11-29 公开号: CN106676108A

9. 乳酸乳球菌乳亚种YF11的非编码小RNAs144
UNIV TIANJIN
QIAO JIANJUN; QI JIAKUN; ZHAO XIULI; LI YANNI; CAIYINQINGGELE; WANG BINBIN; ZHU HONGJI
公开日期: 2017-05-10 申请日期: 2016-11-29 公开号: CN106636093A

10. 一种控制发酵培养体系pH值以提高乳酸链球菌素产量的方法
天津大学
乔建军; 刘家亨; 赵秀丽; 财音青格乐; 吴昊; 朱宏吉
公开日期: 2017-05-10 申请日期: 2016-12-09 公开号: CN106636262A

11. 乳酸乳球菌乳亚种YF11的非编码小RNAs224
UNIV TIANJIN
QIAO JIANJUN; ZHOU DANDAN; ZHAO XIULI; ZHU HONGJI; CAIYINQINGGELE; LI YANNI; WU HAO
公开日期: 2017-03-22 申请日期: 2016-11-29 公开号: CN106520770A

12. 乳酸乳球菌乳亚种YF11的非编码小RNAs224
UNIV TIANJIN
CAIYINQINGGELE; QIAO JIANJUN; ZHOU DANDAN; ZHAO XIULI; LI YANNI; ZHU HONGJI; WU HAO
公开日期: 2017-03-22 申请日期: 2016-11-29 公开号: CN106520770A

13. 从大豆中分离到的种子特异性启动子序列及其应用
南开大学
李明春; 财音青格乐; 邢来君; 蔡易; 陶然
公开日期: 2004-10-20 申请日期: 2003-10-23 公开号: CN1537861C

主持完成2项国家自然科学基金项目、1项“863”子课题项目、1项国家重点研发项目子课题和1项天津市自然科学基金项目，参与多项国家自然科学基金项目、科技部重点研发项目和省部级科研项目。

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