朱宏吉 副教授 博士 天津市 研究领域: 生物医药 研究方向: 生物质利用;制药工艺与装备 所在单位: 天津大学

基本信息

所在单位:
天津大学
机构细分:
合成生物与生物制造学院
单位类型:
高等院校
职务:
副教授
职称:
副教授
最高学历:
博士
专家荣誉:
天津市科学技术进步奖,2017年度(2017JB-3-098-R3),三等奖,食用菌废弃菌糠的综合利用,天津大学,乔建军,朱宏吉

科研能力

研究领域:
生物医药
研究方向:
生物质利用;制药工艺与装备
论文著作:
1. Mengyuan Li , Ruiqi Chen , Jianjun Qiao , Weiguo Li , Hongji Zhu *. Recent Advances in Multiple Strategies for the Biosynthesis of Sesquiterpenols. Biomolecules. 2025 May 3;15(5):664
2. Ziqiang Chen,Wenqing Liu,Shenyi Zhang,Yushen Song,Zixuan Zhang,Guanning Yao, Guang-Rong Zhao,Hongji Zhu, Jianjun Qiao,Hui Zhao,Jiaheng Liu.Harnessing soybean okara for enhanced microbial production of indigoidine.Bioresource Technology. 2025,434: 132808
3. Pingqiu Jian,Jiaheng Liu,Li Li,Qianqian Song,Di Zhang,Shenyi Zhang,Chaofan Chai,Hui Zhao, Guangrong Zhao2,Hongji Zhu, Jianjun Qiao. AcrR1, a novel TetR/AcrR family repressor, mediates acid and antibiotic resistance and nisin biosynthesis in Lactococcus lactis F44. Journal of Dairy Science.2024,107:6576-6591
4. Shengli Wang, Chuanling Zhan, Shengxin Nie, Daoguang Tian, Juane Lu, Mingzhang Wen,Jianjun Qiao, Hongji Zhu, and Qinggele Caiyin. J. Agric. Food Chem. 2023, 71:12452−12461
5. Rongrong Huang, Ning Zhi, Lu Yu, Yaoyang Li, Xiangyu Wu, Jiale He, Hongji Zhu, Jianjun Qiao,Xiaohong Liu, Changlin Tian, Jiangyun Wang, and Min Dong. Genetically Encoded Photosensitizer Protein Reduces Iron−Sulfur Clusters of Radical SAM Enzymes. Catalysis. 1/03/2023.
6. Qianqian Song,Hao Wu, Peng Zhang,Kairen Tian,Hongji Zhu. LssR plays a positive regulatory role in acid and nisin tolerance response of Lactococcus lactis.JOURNAL OF DAIRY SCIENCE.2022,105:6483-6498
7. Jiaheng Liu, Hui Xiong, Yuhui Du, Itsanun Wiwatanaratanabutr, Xiaofang Wu, Guangrong Zhao, Hongji Zhu, Qinggele Caiyin, Jianjun Qiao. NisI Maturation and Its Influence on Nisin Resistance in Lactococcus lactis. Applied and Environmental Microbiology. 2020,86:1306-1320.
8. Jiaheng Liu,Huiling Li,Hui Xiong,Xixian Xie,NingChen,Guangrong Zhao, Qinggele Caiyin,Hongji Zhu,Jianjun Qiao.Two‐stage carbon distribution and cofactor generation for improving L‐threonine production of Escherichia coli. BIOTECHNOLOGY AND BIOENGINEERING.2019,116:110-120
9. Zhu Hongji, Tian, Li, Zhang, Lei, Bi, Jingxu, Song, Qianqian, Yang, Hui & Qiao Jianjun. Preparation, characterization and antioxidant activity of polysaccharide from spent Lentinus edodes substrate. International Journal of Biological Macromolecules.2018, 112:976-984.
10. Tian Li, Liu Jiaheng, Ma Li, Zhang Lei, Wang Shipeng, Yan Erfu & Zhu Hongji. Isolation and purification of antioxidant and ace-inhibitory peptides from yak (Bos grunniens) skin. Journal of Food Processing & Preservation. 2017, 41(5).
11. Zhu Hongji, Wang Weihua, Liu Jiaheng, Caiyin, Qinggele & Qiao Jianjun. Immobilization of streptomyces thermotolerans 11432 on polyurethane foam to improve production of acetylisovaleryltylosin. Journal of Industrial Microbiology & Biotechnology. 2015, 42(1):105-111.
12. Zhu Hongji, Liu Jiaheng, Sun Lifan, Hu Zongfu & Qiao Jianjun. Combined alkali and acid pretreatment of spent mushroom substrate for reducing sugar and biofertilizer production. Bioresource Technology, 2013, 136:257-266.
13. Liu Jiaheng, Sun Lifan, Hu Zongfu, Wang Shipeng, Zhu Hongji & Qiao Jianjun. A comparison of low temperature alkali and high temperature acid pretreatments for improving saccharification of spent mushroom substrate. IERI Procedia, 2013, 5:184-188.
14. Zhu Hongji, Sun Lifan, Zhang Yanfei, Zhang Xiaoli & Qiao Jianjun. Conversion of spent mushroom substrate to biofertilizer using a stress-tolerant phosphate-solubilizing Pichia farinose FL7. Bioresource Technology. 2012, 111(5):410-416.
15. Zhu Hongji, Sheng Kai, Yan Erfu, Qiao Jianjun & Lv Feng. Extraction, purification and antibacterial activities of a polysaccharide from spent mushroom substrate. International Journal of Biological Macromolecules. 2012, 50(3):840-843.
16. Qiao Jianjun, Zhang Yanfei, Sun Lifan, Liu Weiwei, Zhu Hongji & Zhang Zhijun. Production of spent mushroom substrate hydrolysates useful for cultivation of Lactococcus lactis by dilute sulfuric acid, cellulase and xylanase treatment. Bioresource Technology, 2011, 102:8046-8051.
17. Liang Jinhua, Zhu Hongji, Bai Peng, Wang Jingxian. Applications of hybrid process of distillation-pervapouration in chemical industry. Asian Journal of Chemistry, 2011, 10: 4606-4608.
发明专利:
朱宏吉,一种4-羟基苯乙酸3-羟化酶突变体及其应用,CN119752826B,2025-12-02
朱宏吉,4-羟基苯乙酸3-羟化酶突变体与编码基因及应用,CN119639699B,2025-12-02
朱宏吉,用于重金属吸附-菌肥发酵的菌糠再利用耦合装置,ZL2018200198 05.4,2018-09-11
朱宏吉,一种生产微生物乳酸链球菌素的方法,ZL201310065818,2015-01-21
朱宏吉,一种泡腾片式低分子量胶原蛋白肽及其制备方法,ZL201210361765,2014-06-04
朱宏吉,一种微生物固定化方法,2013100658187,2013-10-06
科研项目:
河南中源化学股份有限公司,天然碱加工湿分解技术及日用小苏打技术开发,2020-2022,负责人
天津市科技支撑,香菇菌糠多糖兽药的开发研制(项目编号14ZCZDNC00008),2014-2017,负责人,
国家自然科学基金,高效合成NISIN 乳酸乳球菌的简化基因组构建及其优化(项目编号31270142),2013.1-2016.12,研究骨干
天津市重点基金,食用菌废弃菌糠的综合利用(项目编号09JCZDJC26500),2009-2012,研究骨干
天津市润知生物科技有限公司,胶原蛋白肽提取分离关键技术研究(项目合同编号2012120024003479),2013-2014,负责人
天津市科委农村处,蓟州区废弃菌棒高效综合资源化开发利用 (2017GKF-0605),2017-2019,负责人

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