精细化工

1. 活性天然产物的合成及相关药物化学研究
2. 基于有机电催化不对称转化的手性药物合成

1. Gao, Y.†; Jiang, B.†; Friede, N. C.; Hunter, A. C.; Boucher, D. G.; Minteer, S. D.; Sigman, M. S.; Reisman, S. E.*; Baran, P. S.* Electrocatalytic asymmetric Nozaki–Hiyama–Kishi decarboxylative coupling: scope, applications, and mechanism. J. Am. Chem. Soc. 2024, 146, 4872. (†Equal Contribution)

2. Gao, Y.; Baran, P. S.* Nickel-catalyzed enantioselective decarboxylative acylation: rapid, modular access to α-amino ketones. Angew. Chem. Int. Ed. 2023, e202315203.

3. Gao, Y.; Zhang, B.; He, J.; Baran, P. S.* Ni-electrocatalytic enantioselective doubly decarboxylative C(sp3)–C(sp3) cross coupling. J. Am. Chem. Soc. 2023, 145, 11518.

4. Gao, Y.†; Zhang, B†; Levy, L.; Zhang, H.-J.; He, C; Baran, P. S.* Ni-catalyzed enantioselective dialkyl carbinol synthesis via decarboxylative cross coupling: development, scope, and applications. J. Am. Chem. Soc. 2022, 144, 10992. (†Equal Contribution)

5. Zhang, B†; Gao, Y†; Hioki, Y.; Oderinde, M. S.; Qiao, J. X.; Rodriguez, K. X.; Zhang, H.-J.; Kawamata, Y.; Baran, P. S.* Ni-electrocatalytic C(sp3)–C(sp3) doubly decarboxylative coupling. Nature 2022, 606, 313. (†Equal Contribution)

6. Gao, Y.; Hill, D. E.; Hao, W.; McNicholas, B. J.; Vantourout, J. C.; Hadt, R. G.; Reisman, S. E.*; Blackmond, D. G.*; Baran, P. S.* Electrochemical Nozaki–Hiyama–Kishi coupling: scope, applications, and mechanism. J. Am. Chem. Soc. 2021, 143, 9478.

7. Wang, P.†; Gao, Y.†; Ma, D.* Divergent entry to Gelsedine-type alkaloids: total syntheses of (−)-Gelsedilam, (−)-Gelsenicine, (−)-Gelsedine, and (−)-Gelsemoxonine. J. Am. Chem. Soc. 2018, 140, 11608. (†Equal Contribution)

8. Gao, Y.; Ma, D.* Samarium iodide-mediated C–C bond formation in the total synthesis of natural products. Nat. Synth. 2022, 1, 275.

9. Gao, Y.; Ma, D.* In pursuit of synthetic efficiency: convergent approaches. Acc. Chem. Res. 2021, 54, 569.

10. Gao, Y.; Wei, Y.; Ma, D.* Synthetic studies toward Plumisclerin A. Org. Lett. 2019, 21, 1384.

11. Gao, Y.; Fan, M.; Geng, Q.; Ma, D.* Total synthesis of Lapidilectine B enabled by Manganese(III)‐mediated oxidative cyclization of indoles. Chem. Eur. J. 2018, 24, 6547.